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Advances in 1,3-Propanediol production: A comprehensive review of current strategies, Technologies, and Future Perspectives
Author(s):
1. Su Chern Lim: Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia; Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia; HG Biochemical Sdn. Bhd., Johor Bahru, Johor, Malaysia
2. Yen Min Koh: Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia; Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia; HG Biochemical Sdn. Bhd., Johor Bahru, Johor, Malaysia
3. Solleh Ramli: Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia; Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor, Malaysia
4. Maizatulakmal Yahayu: Faculty of Chemical and Energy Engineering,Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor,Malaysia
5. Ismail Ware: Faculty of Chemical and Energy Engineering,Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor,Malaysia
6. Daniel Joe Dailin: Faculty of Chemical and Energy Engineering,Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor,Malaysia
7. Siti Zulaiha Hanapi: Faculty of Chemical and Energy Engineering,Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor,Malaysia
8. Eng San Lim: HG Biochemical Sdn. Bhd., Johor Bahru,Johor,Malaysia
9. Hesham Ali El-Enshasy: Bioprocess Development Department, City for Scientific Research and Technology Applications (SRTA), New Burg Al Arab,Alexandria,EgyptFaculty of Chemical and Energy Engineering,Universiti Teknologi Malaysia (UTM), 81310, Skudai, Johor,Malaysia
Abstract:
In recent times, there are rising concerns about environmental and economic trends, which have prompted an expanding attention pertaining to ecotechnology. One intriguing approach is the utilization of industrially obtained by-products to produce value-added chemical products through bioprocesses, specifically fermentation process via microbial actions. Among the biological substances produced commercially, 1,3-propanediol (1,3-PDO) has been gaining attention. Although bioprocesses are exceptionally feasible from an environmental and economic perspective, they present a few drawbacks, which are inhibition of product and substrate, accumulation of by-products and low yields. In particular, on account of the production process of 1,3-PDO, intermediates formation such as 3-hydroxypropionaldehyde (3-HPA) and undesired secondary products will lead to cell growth inhibition and eventually cause a decrease in 1,3-PDO yield. In this article, factors influencing 1,3-PDO production was discussed. This review article also explains the background, properties as well as applications of 1,3-PDO, the mechanisms of 1,3-PDO production, including chemical and microbial methods, and the microorganisms for 1,3-PDO production.
Page(s): 638-646
DOI: DOI not available
Published: Journal: Bioscience Research, Volume: 20, Issue: 2, Year: 2023
Keywords:
microorganisms , microbial methods , 3PDO , 3propanediol 1 , chemical methods
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