Vitamin B12, folate and iron levels in primary nocturnal enuresis. | [Pakistan Journal of Medical Sciences • 2015]

Author(s):

1. Sebahattin Albayrak: Department of Urology Bozok University, School of Medicine, Yozgat, Turkey

2. Kürsad Zengin: Department of Urology Bozok University, School of Medicine, Yozgat, Turkey

3. Serhat Tanik: Department of Urology Bozok University, School of Medicine, Yozgat, Turkey

4. Ghaniya Daar: Department of Pediatrics, Bozok University, School of Medicine, Yozgat, Turkey

5. Mustafa Yasar Ozdamar: Department of Pediatric Surgery Bozok University, School of Medicine, Yozgat, Turkey

6. Hasan Bakirtas: Department of Urology Bozok University, School of Medicine, Yozgat, Turkey

7. M. Abdur Rahim Imamoglu: Department of Urology Bozok University, School of Medicine, Yozgat, Turkey

8. Mesut Gurdal: Department of Urology Bozok University, School of Medicine, Yozgat, Turkey

Abstract:

Objective: Folate, vitamin B12 and iron are important vitamin and minerals which play role in the development of nervous system. The aim of this study was looking at the presence of folate, vitamin B12 and iron deficiency among patients with Primary nocturnal enuresis (PNE) and possible relation between the delay of central nervous system (CNS) development, PNE and folate, vitamin B12 and iron states. Methods: Consecutively applied forty patients with PNE (23 girls and 17 boys) and otherwise normal thirty control subjects (17 girls and 13 boys) were included in the study. Average ages (in range) of PNE and the control group were 9.2(6-12) years and 9.3 (6-12) years accordingly. Age, height, weight, complete blood count, blood vitamin B12, folate, ferritin and iron values of both groups were recorded and compared to each other. Results: Average vitamin B12 and folate levels of patients with PNE were significantly and statistically lower compared to those of the control group. Average blood iron of patients with PNE was significantly higher than that of the control group and also average ferritin level of the PNE group was detected to be higher than the control group but this relation was statistically insignificant. Conclusion: Primary nocturnal enuresis is related to the delay in CNS maturation so it was thought that low vitamin B12 and folate which were found in patients with PNE may have role in the delay of CNS maturation. Additionally, further studies are needed to investigate the role of vitamin B12 and folate either alone or as combination in treatment of patients with PNE who have low vitamin B12and folate level.

Page(s): 87-90

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical Sciences, Volume: 31, Issue: 1, Year: 2015

Keywords:

Keywords are not available for this article.

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views