A case of confluence: pericardial effusion unveiling hashimoto's hypothyroidism and atypical systemic lupus erythematosus in a young female with syncope | [Pakistan Heart Journal • 2024]

Author(s):

1. Umar Farooq: Rawalpindi Institute of Cardiology, Rawalpindi, Pakistan

2. Shafaq Saleem: Benazir Bhutto Hospital, Rawalpindi, Pakistan

3. Sana Ahmed: Benazir Bhutto Hospital, Rawalpindi, Pakistan

4. Ahmad Raza: Benazir Bhutto Hospital, Rawalpindi, Pakistan

Abstract:

This case report presents a remarkable convergence of autoimmune diseases in a young female patient who initially presented with syncope and was subsequently diagnosed with pericardial effusion-induced cardiac tamponade. Through meticulous investigation, she was found to have Hashimoto's thyroiditis alongside an atypical presentation of systemic lupus erythematosus (SLE), marked by a unique form of antinuclear antibody positivity. Treatment involved a combination of steroids, immunosuppressants, and thyroid hormone replacement. This intricate association between intersecting autoimmune disorders, with atypical presentations and cardiovascular manifestations, underscores the complexity of autoimmune pathology and the importance of a high index of suspicion in reaching accurate diagnoses.

Page(s): 166-168

DOI: 10.47144/phj.v57i2.2752

Published: Journal: Pakistan Heart Journal, Volume: 57, Issue: 2, Year: 2024

Keywords:

Syncope , Pericardial effusion , Cardiac tamponade , SLE , Hashimotos Hypothyroidism , Atypical Systemic Lupus Erythematosus

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