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Antibacterial and Hemolytic Activities of Brominated 2-Phenitidine Derivatives
Author(s)
Muhammad Athar Abbasi Department of Chemistry, Government College University,Lahore,Pakistan
Amna Saeed Department of Chemistry, Government College University,Lahore,Pakistan
Aziz-ur-Rehman Department of Chemistry, Government College University,Lahore,Pakistan
Sabahat Zahra Siddiqui Department of Chemistry, Government College University,Lahore,Pakistan
Kaniz Rubab Department of Chemistry, Government College University,Lahore,Pakistan
Muhammad Shahid Department of Chemistry and Biochemistry, University of Agriculture,Faisalabad,Pakistan
Fozia Anjum Department of Chemistry, Government College University,Faisalabad,Pakistan
Abstract
The present study describes the antibacterial and hemolytic activities of some brominated 2-phenitidine derivatives. These synthetic molecules were screened against selected bacterial strains, i.e., gram positive and negative using streptomycin as control. The cytotoxicity of these molecules was also tested using triton as reference. The study revealed that the analyzed molecules displayed moderate potential as antibacterial agents; however, these might serve as valued hemolytic agents.
Publication Details
Page(s) 233-237
DOI DOI not available
Published Journal: Proceedings of Pakistan Academy of Sciences, Volume: 52, Issue: 3, Year: 2015
Keywords
cytotoxicity antibacterial agents hemolytic agents 2phenitidine derivatives
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