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An investigation of the anti-diabetic effects of an extract from Cladonia humilis.
Author(s):
1. Yibing Zhang: School of Traditional Chinese Medicine, Chongqing Medical University, Jieqing Road, Huxi University City, Chongqing, PR China
2. Jinli Shi: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China
3. Yong Zhao: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China
4. Haifeng Cui: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China
5. Chunyu Cao: School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China
6. Sha Liu: School of Traditional Chinese Medicine, Chongqing Medical University, Jieqing Road, Huxi University City, Chongqing, PR China
Abstract:
The effect of Cladonia humilis on glycaemic metabolism was researched in this studied. The blood glucose, insulin secretion and glycogen synthesis of the hyperglycemic mice induced by alloxan were analyzed respectively. The gluconeogenesis and the sugar tolerance of the normal mice were also analyzed in this paper. After the hyperglycemic mice were orally administrated with Cladonia humilis extract, the blood glucose was decreased (pCladonia humilis extract could inhibite the gluconeogenesis (pCladonia humilis extract-induced significant decreases of the blood glucose in hyperglycemic mice.
Page(s): 509-512
DOI: DOI not available
Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 25, Issue: 3, Year: 2012
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