The reaction of harmaline with cyclohezanone-oxalyl chloride adduct - A one step synthesis of reserpine analogues. | Journal of Chemical Society of Pakistan 1984

Author(s)

Atta-Ur-Rehman HEJ Postgraduate Institute of Chemistry, University of Karachi, Karachi, Pakistan

S. Firdous HEJ Postgraduate Institute of Chemistry, University of Karachi, Karachi, Pakistan

Abstract

The reaction of cyclohexanon with oxalylchloride affords the adduct (3). Reaction of (3) with harmaline (1) affords a high yield one step synthesis of the pharmacologically interesting skeletal system (5) which bears the carbon frame-work of reserpine

Publication Details

Page(s) 17-26

DOI DOI not available

Published Journal: Journal of Chemical Society of Pakistan, Volume: 6, Issue: 1, Year: 1984

Keywords

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