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Transcranial Pulsed Ultrasound with Alteplase Intravenous Thrombolysis for Vascular Recanalisation in Acute Ischemic Stroke
Author(s):
1. Zhenghong Chen: EEG Room, Linyi Central Hospital of Shandong Province,China
2. Jingyu Zhang: Department of General Surgery, Linyi Central Hospital of Shandong Province,China
Abstract:
The objective of study was to investigate the e ect of transcranial pulsed ultrasound combined with alteplase on treatment of vascular recanalisation in acute ischemic stroke patients. Eighty-two patients were randomly divided equally into two groups. Group A was treated with transcranial pulsed ultrasound combined with alteplase intravenous thrombolysis. Group B received alteplase intravenous thrombolytic treatment. At 2 and 24 hours after treatment, National Institutes of Health Stroke Scale (NIHSS) score of group A was lower than that of group B (both p<0.001), and vascular recanalisation rate of patients in group A was higher than that of group B (p=0.004, and 0.002 respectively). At 90 days after treatment, rate of favourable prognosis [(modi ed rankin scale (mRS) d2 points)] of group A was higher than that of group B (p=0.001). Transcranial pulsed ultrasound combined with alteplase intravenous thrombolytic treatment can improve vascular recanalization rate and prognosis.
Page(s): 765-767
DOI: DOI not available
Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 30, Issue: 7, Year: 2020
Keywords:
acute ischemic stroke , thrombolysis , Alteplase , Vascular recanalisation , Transcranial pulsed ultrasound
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