To Assess the Correlation Between Neutrophil to Lymphocyte Ratio with hS-CRP as Inflammatory Marker in Patients with Chronic Kidney Disease | [ESCULAPIO. JOURNAL OF SERVICES INSTITUTE OF MEDICAL SCIENCES • 2023]

Author(s):

1. Muhammad Awais Abid: Medical Unit IV Services Hospital, Lahore, Pakistan

2. Hafsa Farooq: Arif Memorial Hospital Lahore, Pakistan

3. Maria Qibtia: Medical Unit IV Services Hospital, Lahore, Pakistan

4. Hamna Farooq: Arif Memorial Hospital Lahore, Pakistan

5. Tayyab Mehmood: Medical Unit IV Services Hospital, Lahore, Pakistan

6. Khizar Hayat: Medical Unit IV Services Hospital, Lahore, Pakistan

Abstract:

Objective: To assess the correlation between neutrophil-to-lymphocyte ratio with hs-CRP as an inflammatory marker in patients with chronic kidney disease Material and Methods: This Study was Cross-sectional study and conducted in the Department of Medical Unit-4 Services Hospital, Lahore. Duration of this study was 6 months after Synopsis approval. 115 patients with CKD (by operational definition) with peripheral edema were included in the study. A blood sample was then collected using a 5cc BD syringe under aseptic conditions. All samples were stored in a vial containing Ringer's solution. Then all samples were sent to the hospital laboratory for hs-CRP and NLR assessment. Reports were assessed and hs-CRP and NLR Result: In this study, the correlation coefficient showed a weak positive correlation between hs-CRP and NLR. i.e. r= 0.399, p-value=0.000. Stratification for age, sex, BMI and duration of CKD showed a significant positive correlation between NLR and hs-CRP. Conclusion: Moderately positive correlation between NLR and hs-CRP. Both markers have the potential to exclude persistent subclinical problems and may also perform risk stratification for CKD patients.

Page(s): 414-418

DOI: 10.51273/esc23.25131948

Published: Journal: ESCULAPIO. JOURNAL OF SERVICES INSTITUTE OF MEDICAL SCIENCES, Volume: 19, Issue: 4, Year: 2023

Keywords:

Neutrophil to lymphocyte ratio , hsCRP Chronic kidney disease

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