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A comparative histological study of effects of shisha and cigarettes on trachea of mice.
Author(s):
1. Shazia Imran: Department of Anatomy, IIMC-T, Rawalpindi, Pakistan
2. Rehana Rana: Department of Anatomy, IIMC-T, Rawalpindi, Pakistan
Abstract:
Objective: To determine the comparative histologicaI effects of Shish a and cigarettes on trachea of experimental animals. Study Design: It was an analytical experimental randomized control trial. Place and Duration of Study: The study was carried out in the department of Anatomy, Islamic International Medical College, Rawalpindi, in collaboration with National Institute of Health (NIH), Islamabad. The duration of the study was 6 months. Materials and Methods: 40 adult male BALB/c mice were used and divided into 3 groups. Control group C was kept in a chamber in fresh air. Group SS was exposed to Shisha smoke and Group CS was exposed to equivalent quantity of nicotine by burning cigarettes. All mice were dissected after 8 weeks and tissues of trachea were examined microscopically and results were compared in experimental groups. Results: The trachea was examined for three parameters. There was marked mucus cell hyperplasia and submucosal gland hypertrophy in group SS and the difference between group SS and CS was statistically significant (p
Page(s): 21-26
DOI: DOI not available
Published: Journal: Journal of Islamic International Medical College, Volume: 9, Issue: 2, Year: 2014
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