Abstract:
Cancer is a prevalent problem in modern times and while there are available treatments, it continues to cause a significant number of deaths. Cancer is a complex anomaly of the body that is becoming increasingly difficult to control. In the field of nano medicine, nanoparticles are utilized as a drug transporter. Zinc oxide nanoparticles, in particular, offer flexible platforms for therapeutic and biomedical applications, and have the potential to act as an effective anticancerous drug. To investigate this potential, a study was conducted using Rattus Norvegicus as an animal model. The rats were administered carbon tetrachloride (CCl4) and zinc oxide (ZnO) nanoparticles for fourteen consecutive days. After euthanizing the rats, biomedical tests were performed to verify the therapeutic results of the nanoparticles. Analysis of histopathological slides and morphology revealed visible differences in the vital organ, with liver cirrhosis observed in the rats injected only with carbon tetrachloride compared to those injected with both carbon tetrachloride and zinc oxide nanoparticles. Overall, the study highlights the potential of zinc oxide nanoparticles as a promising anti-cancerous drug, with the need for continued research in the development of new and effective treatments for cancer.
Keywords:
lactate dehydrogenase
,
carbon tetrachloride
,
Liver function
,
Nanoparticles