A laboratory study of susceptibility of methicillin resistant staphylococcus aureus (MRSA) . | [Pakistan Journal of Medical Sciences • 2004]

Author(s):

1. Mulazim Hussain Bukhari: Department of Pathology, KEMC Lahore, Pakistan

2. Abida Iqbal: Department of Pathology, FJMC, Lahore, Pakistan

3. Nizam Khatoon: Department of Pathology, Institute of Public Health, College of Community Medicine, Lahore, Pakistan

4. Nasir Iqbal: Department of Pathology, KEMC, Lahore, Pakistan

5. Samina Naeem: Department of Pathology, KEMC, Lahore, Pakistan

6. G. R. Qureshi: Department of Pathology, KEMC, Lahore, Pakistan

7. I. A. Naveed: Department of Pathology, KEMC, Lahore, Pakistan

Abstract:

To study the mode of infection, incidence of Methicillin resistant Staphylococcus aureus (MRSA) and their susceptibility against glycopeptides and Fucidic acid, so that awareness may be created for consultants against such notorious rapidly spreading bacteria and recommendation can be made for their prevention and control. 350 S.aureus Strains were isolated from 1800 random clinical specimens. 135 MRSA out of these cultures were selected for determining susceptibility to Vancomycin, Teicoplanin R Fucidic acid. The samples were processed in the Department of Pathology, King Edward Medical College, Lahore, during June 2000 -December 2000. The specimens from various infections suspected on clinical ground were processed by Standard methods and antibiotic susceptibility testing of all the 350 S.aureus and 135 MRSA isolates was done by using modified Kirby Bauer Disc diffusion technique. Of 350 positive S.aureus cultures, 135 were found to be Methicillin resistant (38.5%) which showed susceptibility 96%, 94% and 86% to Vancomycin, Teicoplanin and Fucidic acid respectively. This study showed a high incidence of MRSA at Mayo Hospital Lahore. Glycopeptides and Fucidic acid were found to be valuable antibiotics against MRSA.

Page(s): 229-233

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical Sciences, Volume: 20, Issue: 3, Year: 2004

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