Abstract:
The Dehydration hypothesis on aging has been extended to life processes involving small and large quantities of food intake. It is suggested that large quantities of food dehydrates the system and thus deactivates, at least partially, the digestive enzymes. Variation in the electrolytic balance is noted among fasting volunteers and it is observed that large intake of food increases the electrolyte concentration in their blood sera which returns to normal after fasting is over. Large food intake is also responsible for increase in glucose level which, if not adequately metabolised, enters into glycation reactions. The latter lead to cross-link formation on the one hand and dehydration on the other hand. This explains the formation of the aging complexes such as plaques and osteophytes at stressed sites which themselves have a low hydration level.
Page(s):
16-22
DOI:
DOI not available
Published:
Journal: Hamdard Medicus, Volume: 33, Issue: 4, Year: 1990