The Effect of Iron Deficiency Anemia on the Course and Outcome of Pregnancy | [Archives of Pharmacy Practice • 2024]

Author(s):

1. Liliia Adelevna Khanipova: Department of Therapy, Faculty of Medicine, Institute of Clinical Medicine named after N. V. Sklifosovsky, The First Moscow State Medical University named after I. M. Sechenov, Moscow, Russia.

2. Taisiia Vladimirovna Mandzhieva: Department of Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia.

3. Aminat Aubekirovna Karaketova: Department of Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia

4. Anna Alievna Omarova: Department of Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia

5. Anna Alievna Rasulova: Department of Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia

6. Milena Osmanovna Meremkulova: Department of Therapy, Faculty of Medicine, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia

7. Zarina Timurovna Mambetova: Department of Therapy, Faculty of Medicine, North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia-Alania, Russia.

Abstract:

Iron deficiency anemia is a serious public health problem among pregnant women. Iron is an important element involved in various physiological functions and cellular activity. It is a cofactor of many enzymes and is involved in the oxygen transfer by hemoglobin in erythrocytes, as well as in various cellular processes, including DNA synthesis and redox reactions. In addition, iron deficiency in the early stages alters the structure and metabolism of brain cells. Insufficient iron levels lead to a decrease in the function of enzymes and a decrease in the production of red blood cells, followed by a decrease in the supply of oxygen to tissues. During pregnancy, a woman's need for iron increases for the growth of the fetoplacental complex, the synthesis of maternal erythrocytes, an increase in plasma volume, and, as a result, compensation for iron loss during childbirth. Unidentified and untreated iron deficiency anemia can hurt the health of both mother and fetus. At the same time, the consequences for both the young mother and the child may differ significantly depending on the severity and duration of anemia, as well as the period of pregnancy at which it occurred. The most common complications are a high risk of premature birth and low newborn weight, and cases of intrauterine death of a child are also not uncommon. Timely detection and treatment of mild anemia is extremely important, which will help prevent the development of severe anemia.

Page(s): 7-9

DOI: 10.51847/B0NUqGf6GX

Published: Journal: Archives of Pharmacy Practice, Volume: 15, Issue: 3, Year: 2024

Keywords:

Pregnancy , Iron deficiency , iron deficiency anemia , Premature Birth , Intrauterine mortality

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