To assess the aggressiveness of oral squamous cell carcinoma in the young population | [Journal of Pakistan Medical Association • 2022]

Author(s):

1. Shafqat Ali Shaikh: Department of Otolaryngology and Head and Neck Surgery, Patel Hospital, Karachi, Pakistan.

2. Syed Akbar Abbas: Department of Otolaryngology and Head and Neck Surgery, Aga Khan University Hospital, Karachi, Pakistan.

3. Muhammad Ehteram Ul Haq: Department of Surgery and Allied, The Kidney Centre, Karachi, Pakistan.

4. Bushra Ayub: Department of Surgery and Allied, Patel Hospital, Karachi, Pakistan.

5. Talha Ahmed Qureshi: Department of Otolaryngology and Head and Neck Surgery, Patel Hospital, Karachi, Pakistan.

6. Amna Khalil: Department of Otolaryngology and Head and Neck Surgery, Dow University of Health Sciences, Karachi, Pakistan

Abstract:

Objective: To assess the recurrence and disease-free survival in oral squamous cell carcinoma patients, and to compare them between two age groups. Method: Data were extracted from Patel hospital cancer registry database of patients admitted from January 1st2008 to December 31st 2018 based on retrospective diagnosed with oral squamous cell carcinoma. Patient stratified in to two groups i.e. patients with less than or more than 40 years. Various etiological factors, staging, treatment, site of the tumor and recurrence and mortality were assessed. Results: Of the 450 patients, 124(27.5%) were in group A and 327(72.5%) were in group B. There were 101(81%) males in group A and 240(73.4%) males in group B. The overall mean age was 43.63±10.75 years (range: 22-70 years). The most common site of the tumour was cheek 232(51.5%). Recurrence of tumour was 45(36%) in group A and 120(37%) in group B (p=0.653). Overall mortality in group A was 67(54%) compared to 168(51%) in group B (p=0.811). Conclusion: Mortality and disease recurrence in both age groups was almost the same. Cheek was the most common site of presentation.

Page(s): 1937-1941

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 72, Issue: 10, Year: 2022

Keywords:

Survival , Recurrence , SSC , Oral Cavity , Young age

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