Author(s):
1. Sajad Ahmad Salati:
Department of Surgery, Unaizah College of Medicine, Qassim University, Saudi Arabia.
2. Leenah Abdullah Alqarawi:
Department of Surgery, Unaizah College of Medicine, Qassim University, Saudi Arabia.
3. Yomna Fozan Alquraishi:
Department of Surgery, Unaizah College of Medicine, Qassim University, Saudi Arabia.
Abstract:
Acanthosis nigricans (AN) is a velvety, hyperpigmentation of the skin that usually occurs in intertriginous areas. AN is most commonly associated with benign disorders like diabetes, insulin resistance, endocrinopathies and exogenous medications, but can be a valid cutaneous marker of a wide range of internal malignancies, which makes it important for the physicians across specialties to have awareness about it. With an increase in the prevalence of obesity and diabetes in recent decades, the prevalence of AN has also shown a significant increase. This article will review in detail the epidemiology, pathophysiology, clinical features and treatment of acanthosis nigricans in the light of the literature.
Page(s):
273-288
DOI:
DOI not available
Published:
Journal: Journal of Pakistan Association of Dermatologists, Volume: 31, Issue: 2, Year: 2021
Keywords:
Obesity
,
Insulin resistance
,
hyperpigmentation
,
differential diagnosis
,
paraneoplastic syndrome
,
endocrine disorders
,
Acanthosis nigricans AN
,
growth factors
References:
References are not available for this document.
Citations
Citations are not available for this document.