Utility of Direct Coomb's test in a Tertiary Care Nursery | [Pakistan Armed Forces Medical Journal • 2023]

Author(s):

1. Mussab Ahmad: Department of Neonatology, Fatima Memorial Hospital,Lahore,PakistanFatima Memorial Hospital,Lahore,Pakistan

2. Zahid Anwar: Department of Neonatology, Fatima Memorial Hospital,Lahore,PakistanFatima Memorial Hospital,Lahore,Pakistan

3. Rafia Gul: Department of Neonatology, Fatima Memorial Hospital,Lahore,PakistanFatima Memorial Hospital,Lahore,Pakistan

4. Tahreem Munir: Department of Anesthesia, Mayo Hospital,Lahore,PakistanDepartment of Neonatology, Fatima Memorial Hospital,Lahore,PakistanFatima Memorial Hospital,Lahore,Pakistan

5. Furqan Saleem: Department of Neonatology, Fatima Memorial Hospital,Lahore,PakistanFatima Memorial Hospital,Lahore,Pakistan

6. Saima Pirzada: Department of Neonatology, Fatima Memorial Hospital,Lahore,PakistanFatima Memorial Hospital,Lahore,Pakistan

Abstract:

Objective: To document the causes and clinical significance of direct Coomb's test distal convoluted tubule in neonatal Jaundice at a tertiary care setup. Study Design: Cross-sectional study. Place and Duration of the Study: Fatima Memorial Hospital, Lahore Pakistan, from Nov 2019 to Oct 2020. Methodology: All babies born to “O” or Rh-negative blood group mothers were included. In addition, data including demographics, mother's blood group, baby's blood group, direct Coomb's test results, bilirubin values, and need for treatment was recorded. Results: The study included 989 neonates. Of all, 489(49.4%) were male, the mean birth weight was 2.80±0.75 kg, and the mean gestation was 36±4.3 weeks. ABO mismatch was present in 452(45.7%) cases and Rh mismatch in 123(12.4%). Of all, 58(5.9%) had positive direct Coomb's test. Amongst the positive direct Coomb's test patients, 44(75.8%) babies needed treatment, of which 40(90.9%) received phototherapy, and 4(6.8%) needed Intensive phototherapy (360 degrees). No baby needed an exchange transfusion. Conclusion: In most cases, positive direct Coomb's test was due to ABO blood group incompatibility. In addition, early phototherapy can control bilirubin rise in most cases, so few would need aggressive or intensive treatment.

Page(s): 724-726

DOI: 10.51253/pafmj.v73i3.7640

Published: Journal: Pakistan Armed Forces Medical Journal, Volume: 73, Issue: 3, Year: 2023

Keywords:

Neonatal jaundice , Rh mismatch , ABO mismatch , Direct Coombs test

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views