TESTOSTERONE LEVELS IN PATIENTS OF ERECTILE DYSFUNCTION WITH AND WITHOUT TYPE 2 DIABETES MELLITUS | [Pakistan Journal of Physiology • 2020]

Author(s):

1. Javaid Hassan: Department of Physiology,Kohat Institute of Medical Sciences. Kohat, Pakistan

2. Shafiq-ur-Rehman: Department of Physiology, Muhammad College of Medicine,Khyber Medical College,Peshawar.Pakistan

3. Inayat Shah: Khyber Medical University, Peshawar,Pakistan

4. Muhammad Irfan Shereen: Khyber Medical University, Peshawar,Pakistan

5. Zain-ul-Abideen: Kohat Institute of Medical Sciences. Kohat, Pakistan

6. Henna Salman: Khyber Medical College, Peshawar, Pakistan

Abstract:

Background: There is strong association of erectile dysfunction with age and level of testosterone. The objective of the present study was estimation and comparison of testosterone levels in erectile dysfunction (ED) patients with/without type 2 diabetes mellitus (T2DM). Methods: A comparative cross-sectional study conducted at Khyber Teaching Hospital and Government Naseerullah Babar Memorial Hospital, Peshawar. Male patients of ED, aged 30 to 65 years, with or without diabetes mellitus, were included in the study. Patients with active co-morbidities and unmarried patients were excluded. Assessment of serum testosterone levels (total and free) was done in all subjects. Data was analyzed using SPSS-23. Mean and Standard Deviation were calculated. Independent sample t-test was performed for comparison between the two groups. The severity of ED was assessed using SHIM score. Results: Majority of patients were 40?49 years old (44.5%). Duration of erectile dysfunction was higher in diabetic patients compared to non-diabetics. The total testosterone in serum of diabetics with ED was 493.09±24.9 ng/dL, and 499.53±23.83 in non-diabetic ED patients. Free testosterone was significantly low in diabetic group (p<0.05). Free testosterone was significantly lower in diabetic patients of our study as compared to the non-diabetic ED patients (59.07 pg/ml vs 68.25 pg/ml respectively), (p=0.049). Conclusion: There was no significant difference between the testosterone levels of the two groups. However, free testosterone was significantly reduced in type 2 diabetics compared to non-diabetics with ED.

Page(s): 3-5

DOI: DOI not available

Published: Journal: Pakistan Journal of Physiology, Volume: 16, Issue: 4, Year: 2020

Keywords:

Diabetes Mellitus , testosterone , T2DM , Erectile dysfunction , ED

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views