Abstract:
Herbal medicines are widely used in developing countries and are of greatdemand for primary medical assistance because of their traditional acceptance,low cost and minimum side effects therefore, they have extremely high extentof compatibility with in body. Nannorhops ritchiana Griff (Arecaceae) is aclumping palm, edible and frequently used xerophytic shrub to small treedispersed in Pakistan. In current study, phytotoxicity assessment of Nannorrhopsritchiana leaves extract was evaluated through Radish seed germination assay,cytotoxicity was determined by performing Brine shrimp lethality assay, andantioxidant activity was measured by using 2,2-diphenyl-1- picrylhydrazy(DPPH) free radical scavenging assay as well as qualitative phytochemicalscreening was carried out for the evaluation of bioactive compounds that wereresponsible for toxicity. The results showed that the methanol leaf extract ofNannorrhops ritchiana acquired significant phytotoxicity with radish root lengthinhibition of 80%. Qualitative phytochemical screening revealed that thepresence of alkaloids, flavonoids, saponins, carbohydrates, tannins, terpenoids,polyphenol, phenolic compounds, glycosides, aminoacids and absence ofanthraquinones. The extract had moderate cytotoxic effects for brine shrimp withthe LD50 of 252.1 µgml¯¹. Moreover, the methanol leaf extract exhibited strongantioxidant activity for DPPH with IC50 value of 3.816 µgml¯¹ that indicatestheir significant use for the cure of oxidative stress-related ailments.
Page(s):
62-62
DOI:
DOI not available
Published:
Journal: 4th International Conference of Sciences “Revamped Scientific Outlook of 21st Century, 2025” , November 12,2025, Volume: 1, Issue: 1, Year: 2025
Keywords:
cytotoxicity
,
phytotoxicity
,
antioxidant
,
Nannorrhops ritchiana