Synthesis, characterization and evaluation of a potential of piperidine substituted heterocyclic compounds | Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23 2023

Author(s)

Sadaf Naz Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

Shazia Haider Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

Muniba Inam Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

Ammara Khalid Dept. of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi, Karachi, Pakistan

Abstract

During last few decades there have been extensive research work on Piperidine and Piperidine substituted compounds have been carried out to evaluate their potential as pharmacological and biologically active agents. A number of Piperidine substituted derivatives have been synthesized and characterized by different spectral techniques (EIMS, NMR, UV, FTIR). Analgesic potential of these compounds have been carried out using Eddy’s Hot Plate method and Acetic Acid induced Writhing test. Most of the compounds showed encouraging results, when compared to standard drug Pethidine Hydrochloride . This class can be selected for further studies at molecular level to completely screened its potential.

Publication Details

Page(s) 236-236

DOI DOI not available

Published Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023

Keywords

analgesic piperidine Writhing test Eddys method Pethidine Hydrochloride

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