Triterpenoid Saponins from the Methanol extract of Ocimum basilicum aerial parts. | [Journal of Chemical Society of Pakistan • 2016]

Author(s):

1. Shazia Habib: HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Karachi, Pakistan

2. Bina Shaheen Siddiqui: HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Karachi, Pakistan

3. Sabira Begum: HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Karachi, Pakistan

4. Huma Aslam Bhatti: HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Karachi, Pakistan

Abstract:

Effect of Ocimum basilicum methanol aerial parts extract, its fractions and three pure compounds ursolic acid, 3-epi-ursolic acid and oleanolic acid on human cancer cell lines HT-144, MCF-7, NCI-H460 and SF-268 cell lines using Sulforhodamine B assay was reported earlier by this group. As a result of further phytochemical studies, one new (ocimuside, 1) and one known (ilexoside, 2) triterpenoid saponins were isolated from the methanol extract of the aerial parts of Ocimum basilicum. The structure of the new compound, ocimuside (1) was elucidated by spectroscopic techniques. This may be noted that this is the first report of isolation and structure elucidation of saponins from Ocimum basilicum, although earlier phytochemical analysis indicated the presence of saponins in Ocimum basilicum and other species of this genus.

Page(s): 1014-1017

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 38, Issue: 5, Year: 2016

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