Acute myeloid leukemia, epidemiology and seasonality, a single center experience. | [Biomedica • 2015]

Author(s):

1. A. Ehsan: Fatima Memorial Medical and Dental College, University of Health Sciences, Lahore, Pakistan

2. M. A. Khan: Sheikh Zayed Postgraduate Medical Institute, Lahore, Pakistan

3. A. Lone: Fatima Memorial Medical and Dental College, University of Health Sciences, Lahore, Pakistan

4. M. Arif: Sheikh Zayed Postgraduate Medical Institute, Lahore, Pakistan

5. M. J. Asif: Sheikh Zayed Postgraduate Medical Institute, Lahore, Pakistan

6. S. Riaz: Fatima Memorial Medical and Dental College, University of Health Sciences, Lahore, Pakistan

Abstract:

Background and Objectives: In this study we retrospectively evaluated data of acute myeloid leukemia (AML) patients diagnosed at our center over a span of 7 years. The data was categorized according to FAB classification and then studied for demographic features and for any evidence of seasonality. Methods: This was a cross sectional study conducted at Shaikh Zayed Medical Complex (SZMC), Lah-ore. In this study we retrospectively evaluated data of AML patients diagnosed over a span of 7 years from 1st July 2001 to 30th June 2008. The data was categorized according to FAB classification and stu-died for demographic features. We also analysed the cohort for number of acute myeloid leukemias pre-senting in each month of the year to assess for any evidence of seasonality. Results: Ninety eight patients of AML were studied, 55 males and 43 females. Eleven patients belonged to the paediatric age group with a male to female ratio of 1.2:1; and 87 were adults, male to female ratio of 1.28:1. The mean age of the entire cohort was 37.08 ± 21.63 years. For adult cases the mean age came to 40.93 ± 19.91 years and for paediatric group the mean age was 7.33 ± 4.05 years. M2 category was most common (38 cases) and collectively M2 and M4 contributed 57% of the entire cohort. Monthly distribution of cases showed a prominent peak (30 cases, 30.5%) in the months of September and Octo-ber. M2 and M4 collectively contributed 22 out of these 3o cases (p value

Page(s): 219-222

DOI: DOI not available

Published: Journal: Biomedica, Volume: 31, Issue: 3, Year: 2015

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