Acute Rheumatic Fever (ARF) in a patient of Chronic Mucocutaneous Syndrome or Mucocutaneous Candidiasis having Diarrhea and Skin Rash | [Pakistan Journal of Medical and Health Sciences • 2023]

Author(s):

1. FURQAN UL HAQ: Department of Physiology, Swat Medical College,,Pakistan

2. MUQSIT ALI SHAUKAT: Hayatabad Medical Complex, Peshawar, Pakistan

3. HAMZA YUNUS: Hayatabad Medical Complex, Peshawar, Pakistan

4. SAHIBZADA MUHAMMAD QASIM: Ayub Medical Complex,Abbottabad,Pakistan

5. TANVEER HAMID: Department of Internal Medicine, Sligo General Hospital,Sligo,Ireland

6. IHTISHAM QAYUM: Dudley group NHS Foundation, Dudley DY1 2HQ, United Kingdom

7. SYED SADAM HUSSAIN: Department of Internal Medicine, Hayatabad Medical Complex,Peshawar,Pakistan

8. SOHAIL AHMAD: General Medicine, Lady Reading Hospital,Peshawar,Pakistan

9. ASAD RIAZ: Hayatabad Medical Complex, Peshawar, Pakistan

10. QAZI MUHAMMAD FAROOQ WAHAB: Khyber Teaching Hospital,Peshawar,Pakistan

Abstract:

SUMMARY Acute Rheumatic fever (ARF) is the most common cause of acquired heart disease in the developing world. It is an immunological reaction to group A beta-hemolytic streptococcus Pyogenes. It occurs 2-4 weeks after group A streptococcal pharyngitis due to the development of antistreptococcal antibodies that cross-react with antigens in various tissues of the body, especially cardiac and basal ganglia neuronal antigens. Clinical features of acute rheumatic fever include fever, joint pain, myocarditis, nodules in subcutaneous tissue, Erythema Marginatum, and chorea. Patients with immunodeficiency like mucocutaneous candidiasis are especially prone to recurrent mucocutaneous infections (tonsillopharyngitis, thrush, skin abscess), which can predispose to acute rheumatic fever and subsequent development of rheumatic heart disease over the years.

Page(s): 229-231

DOI: 10.53350/pjmhs2023171229

Published: Journal: Pakistan Journal of Medical and Health Sciences, Volume: 17, Issue: 1, Year: 2023

Keywords:

Acute rheumatic fever , skin rash , chronic mucocutaneous syndrome

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