Urticaria and the role of antihistamines in pruritus. | [Journal of Pakistan Association of Dermatologists • 2004]

Author(s):

1. Jayakar Thomas: Department of Dermatology, Apollo Hospital, & Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India, West Mada church Road, Royapuram, Chennai, 600013, India

Abstract:

Urticaria is a group of reactive disorders of heterogeneous etiology. It can be immunologic or non-immunologic in pathogenesis. Amongst the idiopathic group, autoimmunity may be incriminated where anti-FcεlgE IgG are produced. Histamine, kinins, and eicosanoids are the major inflammatory mediators. Urticaria remains a therapeutic challenge for dermatologists. In spite of recent advancements in the etiopathogenesis and pharmacotherapy, antihistamines still remain the pivotal treatment. The review highlights the role of antihistamines in the management of urticaria.

Page(s): 87-92

DOI: DOI not available

Published: Journal: Journal of Pakistan Association of Dermatologists, Volume: 14, Issue: 0, Year: 2004

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