A 10-year review of histopathological findings of enucleated eyes from a tertiary-care center, Pakistan | [Journal of Pakistan Medical Association • 2020]

Author(s):

1. Rashid Baig: Department of Ophthalmology, Aga Khan University Hospital, Karachi, Pakistan

2. Nasir Uddin: Department of Pathology, Aga Khan University Hospital, Karachi, Pakistan

3. Sidra Zafar: Department of Ophthalmology, Aga Khan University Hospital, Karachi, Pakistan

4. Khabir Ahmad: Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan

5. Arsalan Ahmed: Department of Pathology, Aga Khan University Hospital, Karachi, Pakistan

Abstract:

Objective: To determine the histopathology of enucleated eye specimens. Methods: The 10-year inventory was conducted at Aga Khan University Hospital, Karachi, and comprised all histopathology reports of enucleated eye specimens received from January 2007 to December 2016 by the Section of Histopathology, Department of Pathology. SPSS 19 was used for data analysis. Results: A total of 232 ocular tissue specimens from 231 patients were evaluated. Ocular tumours were the most common histopathological diagnosis 186(80%). Among tumours, retinoblastoma was the most common 137(59%) followed by malignant melanoma 31(13%) and squamous cell carcinoma 15(6.5%). Overall, 16(6.9%) specimens had degenerative changes secondary to different ocular disorders. Staphyloma and Coat's disease was diagnosed in 3(1.3%) cases each. In 4(1.7%) cases, there was no formal diagnosis. Conclusions: Early identification of tumours may allow for conservative management and limit the need for enucleations.

Page(s): 289-292

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 70, Issue: 2, Year: 2020

Keywords:

histopathology , Enucleations , Ocular tumours

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