The Applications of Flow Injection Analysis Coupled with Luminol chemiluminescence in Basic Medium. | [Journal of Chemical Society of Pakistan • 2018]

Author(s):

1. Attiq Ur Rehman Kakar: Department of Chemistry, University of Balochistan, Quetta, Pakistan

2. Naqeebullah Khan: Department of Chemistry, University of Balochistan, Quetta, Pakistan

3. Amir Waseem: Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan

4. FazalUr Rehman: Department of Microbiology, University of Balochistan, Quetta, Pakistan

Abstract:

Summary: Chemiluminescence has appealed significant attention in multidisciplinary diagnostic research fields and revealed various encouraging applications due to its unique selective and sensitive nature. This paper provides a comprehensive review about the principles of flow injection analysis (FIA) and the important parameters regarding the technique. The ideology of chemiluminescence (CL), luminol (Lu) as a CL reagent and its applications in basic medium (liquid-phase) when coupled with FIA as a diagnostic tool in diverse fields of analytical chemistry have been described. The data of 107 papers, which appeared in the literature from 2013 to present (up to our access) for the determination of vital analytes in diverse sample matrices in terms of chemical reaction, sample matrix, analyte, dynamic linear range, limits of detection, sample throughput and coefficient of determination is presented in the tables. The reactions based on FILu-CL involved in mechanistic and chemical studies of medically important substances have also been reviewed. The use of nanotechnology has improved the analytical and diagnostic characteristics of FI-CL strategies by improving the detection limits and further advancements are expected in future with the discovery of new synthetic nano-particles.

Page(s): 1103-1118

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 40, Issue: 6, Year: 2018

Keywords:

Keywords are not available for this article.

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