UROPATHOGEN ISOLATES AND THEIR ANTIBIOTIC SENSITIVITY IN PATIENTS WITH INDWELLING CATHETER ASSOCIATED URINARY TRACT INFECTIONS | [Journal of Postgraduate Medical Institute • 2020]

Author(s):

1. Atta Muhammad Khan: Lady Reading Hospital, MedicalTeaching Institution, Peshawar, Pakistan

2. Zafar Ali: Lady Reading Hospital, MedicalTeaching Institution, Peshawar, Pakistan

3. Ghazi Sultan Salahuddin: Lady Reading Hospital, MedicalTeaching Institution, Peshawar, Pakistan

4. Nowsherwan: Lady Reading Hospital, MedicalTeaching Institution, Peshawar, Pakistan

5. Musharaf Kamal: Lady Reading Hospital, MedicalTeaching Institution, Peshawar, Pakistan

6. Muhammad Asghar: Lady Reading Hospital, MedicalTeaching Institution, Peshawar, Pakistan

7. Muhammad Abdur Rahman Afridi: Lady Reading Hospital, MedicalTeaching Institution, Peshawar, Pakistan

Abstract:

Objective: To determine the frequency of uropathogen isolates and their ancal Teaching Institution, Pesha- tibiotic sensitivity against commonly prescribed antibiotics in patients with inAwdardr-esPsafkoisrtaCno.rrespondence: dwelling catheter associated UTIs (CAUTIs) in our institution. Dr. Zafar Ali Methodology: Our study was carried out at the Departments of Internal MedAssistant Professor, icine and Nephrology, Lady Reading Hospital (LRH), Peshawar, from July 2018 Department of Medicine, Lady to December 2018. It was a descriptive cross sectional study. Patients of both Reading Hospital, Medical genders with UTI and who were catheterized with age ranging from 16 to 65 Teaching Institution, Peshawar years were included through consecutive (non-probability) sampling tech- Pakistan. nique. Specimens, catheter tip, were obtained under strict aseptic techniques Email: ali_zafar1973@yahoo. to detect common bacterial isolates and their sensitivities against commonly com prescribed antibiotics. Data were analyzed via SSPS version 20. Date Received: November 26, 2019 Date Revised: July 03, 2020 Date Accepted: July 10, 2020 Results: There were total 179 catheterized patients. Among them, 67% patients were female. Mean age was 47 ±2.15 years. Sixty six (37%) patients had catheter associated UTI and among them 42 (63.64%) patients were female. Escherichia coli was found in 37% patients followed by Klebsiella pneumoniae in 20% patients. Meropenem and piperacillin-tazobactum had highest sensitivity (89%) in patients with CAUTIs. Conclusion: One-third of our patients had catheter associated urinary tract infection and the most frequent bacteria found was Escherichia coli followed by Klebsiella pneumoniae. A higher resistance was found to the commonly prescribed antibiotics.

Page(s): 68-73

DOI: DOI not available

Published: Journal: Journal of Postgraduate Medical Institute, Volume: 34, Issue: 1, Year: 2020

Keywords:

antibiotics , Urinary tract infection , coli , Catheter associated UTI , Uropathogens , Catheterization

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