Unveiling the therapeutic prospective of active phytochemicals from fagonia species and potential role of its green synthesized nanoparticles | [Pakistan Journal of Botany • 2024]

Author(s):

1. IFFAT NAYILA: Department of Pharmacy, The University of Lahore Sargodha Campus, Sargodha, Pakistan Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan

2. SUMAIRA SHARIF: Institute of Molecular Biology and Biotechnology, The University of Lahore,Lahore,Pakistan

3. MADEEHA SHAHZAD LODHI: Institute of Molecular Biology and Biotechnology, The University of Lahore,Lahore,Pakistan

4. FARHANA AMAN: Department of Chemistry, The University of Lahore Sargodha Campus.,,Sargodha, Pakistan

5. SAIMA ZAHEER: Department of Chemistry, The University of Lahore Sargodha Campus.,,Sargodha, Pakistan

6. ANUM SAJID: Department of Botany, University of Sargodha,Sargodha,Pakistan

Abstract:

The genus Fagonia of the family Zygophyllaceae consists of species, mostly distributed in tropical-subtropical or warmtemperate regions of the world in different environmental conditions. Fagonia is a convenient herbal medicinal plant with a wide range of therapeutic potentials against different diseases. Numerous studies conducted to explore herbal chemistry and biological functions of Fagonia species. In vivo pharmacological examination of Fagonia species revealed noteworthy characteristics like cytotoxic and anti-cancer potential. Novel chemical ingredients found in the species included flavonoids, alkaloids, terpenoids, vitamins, and nutritional components. Numerous researches conducted on Fagonia species has been compiled in this review study. Using references from significant databases, it comprises a thorough review of the literature about the therapeutic usefulness and bioactivities of several extracts identified from Fagonia species. The areas covered in current review reveal details about the immense medicinal value of the different components of Fagonia species, presence of bioactive constituents as well as therapeutic efficacy of nanoparticles synthesized by using Fagonia plant extract, illustrating the advantages of using nanotechnology and green synthesis nanoformulation of herbal plants.

Page(s): 2295-2303

DOI: 10.30848/PJB2024-6(30)

Published: Journal: Pakistan Journal of Botany, Volume: 56, Issue: 6, Year: 2024

Keywords:

antioxidant , cytotoxicity , Antioxidant , Therapeutic potential , Fagonia species , Nanoformulations

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