Vitamin D Level in Unmarried Females with Polycystic Ovarian Syndrome. | [Journal of Islamic International Medical College • 2016]

Author(s):

1. Fouzia Hanif: Biochemistry Department, Federal Medical & Dental College, Islamabad, Pakistan

2. Abdul Khaliq Naveed: Biochemistry Department, Islamic International Medical College, Riphah International University, Islamabad, Pakistan

3. Amena Rahim: Biochemistry Department, Islamic International Medical College, Riphah International University, Islamabad, Pakistan

4. Fareesa Waqar: Biochemistry Gynae & Obs, Islamic International Medical College, Riphah International University, Islamabad, Pakistan

Abstract:

Objective: To assess and compare the levels of vitamin D in the young unmarried patients of PCOS and healthy females of same age group in population of Rawalpindi. Study Design: A descriptive cross sectional study. Place and Duration of Study: The study was conducted in Gynecology and Obstetrics department of Railway Hospital, Rawalpindi in collaboration with Department of Biochemistry IIMC, Rawalpindi from October, 2014 to April, 2015. Materials and Methods: A sample of 150 young, unmarried females of 16-25 years was enrolled with their written consent in this study. These females were divided into two groups, 50 apparently healthy females and 100 diagnosed patients of polycystic ovarian syndrome selected according to Rotterdam criteria. Vitamin D assay was measured by using 25OH Vitamin D Total Elisa Kit. Data was collected on pre-designed questionnaire. The Data was subjected to SPSS version 21 and analyzed using independent T-test. Results: We had 56% controls and 56% PCOS patients suffering from severe vitamin D deficiency. Women with PCOS showed no significant differences in the vitamin D level (10.618+5.296 ng/ml in patients vs 11.846+7.898 ng/ml in controls, respectively, p=0.324). We also did not find significant association between severity of hypovitaminosis D and clinical symptoms of hyperandrogenism like hirsutism (P=0.669), acne (P=0.480) and alopecia (P=0.317). Conclusion: Hypovitaminosis D is equally common among both PCOS patients and healthy females. There is no difference in the vitamin D level among PCOS and control subjects suggesting that there is no role of vitamin D in the pathogenesis of PCOS.

Page(s): 57-61

DOI: DOI not available

Published: Journal: Journal of Islamic International Medical College, Volume: 11, Issue: 2, Year: 2016

Keywords:

Keywords are not available for this article.

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