A study of serum zinc levels among patients of coronary artery disease conducted in a tertiary care hospital. | [Biomedica • 2013]

Author(s):

1. Shafqat Nazir: Department of Biochemistry, Pathology and Cardiology Quaid-e-Azam Medical College, Bahawalpur, Pakistan

2. Ehsan Ullah: Department of Biochemistry, Pathology and Cardiology Quaid-e-Azam Medical College, Bahawalpur, Pakistan

3. Shahadat Hussain Ch: Department of Biochemistry, Pathology and Cardiology Quaid-e-Azam Medical College, Bahawalpur, Pakistan

4. Syed H Raza Bukhari: Department of Biochemistry, Pathology and Cardiology Quaid-e-Azam Medical College, Bahawalpur, Pakistan

Abstract:

Background: Zinc is an important trace element that has been increasingly implicated in coronary artery disease. The study was designed to compare serum zinc levels in patients of coronary artery disease and healthy controls. Methods: It was a prospective, case control study. A total of 125 male participants were divided into healthy controls (n = 25), Ischaemmic subjects without myocardial infarction (n = 50) were included in the study. The serum zinc was analysed by atomic absorption spectrophotometery. Results: The mean age in the ischaemic heart disease patients without infarction (Group - A) and with infarction was comparable to the mean age of control group. Family history of ischaemic heart disease and history of smoking were more common among disease groups as compared to controls. Serum zinc levels were found to be significantly low in study sub-group B2 (83.68 ± 5.55 µg/dl) as compared to control group (99.16 ± 5.18 µg/dl) and remaining study groups showed insignificant differences. Conclusion: Decreased serum zinc levels are associated with coronary artery disease especially the acute myocardial infarction.

Page(s): 136-138

DOI: DOI not available

Published: Journal: Biomedica, Volume: 29, Issue: 3, Year: 2013

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