Abstract:
Background: Trachoma is caused by a bacterium Chlamydia trachomatis. The objective of this study was to evaluate the effectiveness of an alternative regimen of oral azithromycin for the treatment of active trachoma against WHO recommended regimen. Material & Methods: This cross-sectional study was conducted at Khano Eye Hospital, Lakki Marwat, Khyber Pakhtunkhwa, from January 2008 to December 2008. Sixty patients with active trachoma were included. Those with advanced trachomatous complications like trichiasis and corneal opacity were excluded. Patients were randomly assigned to two groups of 30. Group A received oral azithromycin one gram stat, while Group B was given oral azithromycin 500 mg daily for 3 days. Success of regimen was defined as disappearance of discharge and improvement of “off & on” defective vision at 2 weeks. Descriptive and inferential statistics were applied. P0.05). Conclusion: Oral azithromycin 500 mg daily for three days may be used safely and effectively for the treatment of active trachoma.
Page(s):
224-226
DOI:
DOI not available
Published:
Journal: Gomal Journal of Medical Sciences, Volume: 11, Issue: 2, Year: 2013