Utility of Routine Gall Bladder Histopathology after Living Donor Hepatectomy in Liver Transplantation. | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2018]

Author(s):

1. Abu Bakar Hafeez Bhatti: Department of HPB Surgery and Liver Transplantation, Shifa International Hospital, Islamabad, Pakistan

2. Ihsanul Haq: Department of HPB Surgery and Liver Transplantation, Shifa International Hospital, Islamabad, Pakistan

3. Imran Nazir Ahmed: Department of Pathology, Shifa International Hospital, Islamabad, Pakistan

4. Raenah Bilal: Department of HPB Surgery and Liver Transplantation, Shifa International Hospital, Islamabad, Pakistan

5. Faisal Saud Dar: Department of HPB Surgery and Liver Transplantation, Shifa International Hospital, Islamabad, Pakistan

Abstract:

Intraoperative cholangiogram with cholecystectomy is a routinely performed procedure in living donor liver transplantation (LDLT).The objective of this study was to determine the frequency of gall bladder pathology in healthy living donors and whether routine histopathology can be omitted. This was a retrospective review of 366 donors who underwent donor hepatectomy between 2012 and 2016. Primary outcome of interest was frequency of abnormal histopathology findings in removed gall bladder specimen; and if their distribution was different with respect to gender, age and BMI. Male to female ratio was 2.1:1. Median age was 26 (18-50) years. Median BMI was 23.9 (15.7-35) Kg/m2. The most common finding was chronic cholecystitis in 189 (51.6%). Gall bladder pathology was more frequently seen in donors with BMI >25 Kg/m2, i.e. 69.3 % versus 30.7% (p<0.001). Due to high frequency of abnormal findings, gall bladder should be sent routinely for histopathology in healthy liver donors after cholecystectomy.

Page(s): 490-491

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 28, Issue: 6, Year: 2018

Keywords:

Keywords are not available for this article.

References:

[1] DarFS,BhattiAB,DogarAW, 2015.The travails of setting up a living donor liver transplant program: Experience from Pakistan and lessons learned,Liver Transpl 21 982 -90

[2] KanthanR,SengerJ,AhmedS,ChandraS. Gallbladder, 2015.Cancer in the 21st Century,J Oncol 967472 -

[3] SiddiquiFG,MemonAA,AbroAH,SasoliNA,AhmadL, 2013.Routine histopathology of gallbladder after elective cholecystectomy for gallstones: waste of resources or a justified act?,BMC Surg 13 26 -

[4] AkbulutS,KaragulS,ErtugrulI,AydinC,YilmazM,Yilmaz S, 2015.Histopathologic findings of cholecystectomy specimens in patients who underwent donor hepatectomy for living donor liver transplantation,Transplant Proc 47 1466 -8

[5] WrennSM,CallasPW,Abu-JaishW., 2017.Histopathological examination of specimen following cholecystectomy: Are we accepting resect,discard? Surg Endosc 31 586 -93

Citations

Downloads

Views