A retrospective, observational study to assess the intermediate-term clinical outcomes of COVID-19 patients in a tertiary hospital in Khyber Pakhtunkhwa, Pakistan | [Anaesthesia, Pain and Intensive Care • 2024]

Author(s):

1. Muhammad Sheharyar Ashraf: Department of Anesthesia & Critical Care Unit Lady Reading Hospital-MTI,Peshawar,Pakistan

2. Arishay Hussaini: Department of Critical Care Medicine, Ziauddin University,Karachi,Pakistan

3. Dilanthi Priyadarshani Gamage Dona: Department of Statistics, National Intensive Care Surveillance-MORU (NICS-MORU),Colombo,Sri Lanka

4. Mohiuddin Shaikh: South East Asian Research in Critical Care Health (SEARCH),Karachi,Pakistan

Abstract:

Background & Objective: There is limited data from lower middle-income countries to describe the outcomes of COVID-19 and the prevalence of patients requiring critical care. We aim to assess and compare the demographics, clinical course and mortality of COVID-19 patients admitted to the intensive care unit (ICU) and those admitted to the specialized COVID unit (SCU). Methodology: A single-center, retrospective, observational study in which all patients admitted to Lady Reading Hospital (LRH), Peshawar (Pakistan) with laboratory-confirmed COVID-19 from March 25, 2020 to December 31, 2021 were included. Study data were retrieved through the Pakistan Registry of Intensive Care (PRICE). Results: Of 699 patients, 448 were critically ill, and 251 did not require ICU admission. Of those admitted to ICU, 61.8% were male, with a median age of 55 y. ICU mortality was significantly higher (P = 0.001) among those on IMV and those aged 60 y; whereas 68.9% of the non-ICU patients were male, with a median age of 57 y. While the median duration of hospitalization was significantly longer (P = 0.001), the chances of recovery were substantially better (P = 0.001) compared with the critically ill population. Conclusion: The major risk factors contributing to the increased mortality in COVID-19 patients are age and the requirement for IMV.

Page(s): 198-205

DOI: 10.35975/apic.v28i2.2423

Published: Journal: Anaesthesia, Pain and Intensive Care, Volume: 28, Issue: 2, Year: 2024

Keywords:

COVID19 , SARSCoV2 , Mortality , Intensive care unit , Lower middle income country , Covid19

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