Abstract:
To determine the reliability of ultrasound features in differentiating benign from malignant solid breast masses. A descriptive analytical study conducted at Radiology Department, Aga Khan University Hospital, Karachi, from July 2000 to June 2002. One hundred solid breast masses in females with a tissue diagnosis available were reviewed. Two radiologists reviewed the sonographic features of masses without knowledge of clinical history or histologic examination results. Ultrasound features were corrected later with histologic features to determine the reliability of the former in benign or malignant nature of nodules. Ultrasound features that most reliably characterize masses as benign were a round or oval shape, circumscribed margins and a width to antero-posterior (AP) dimension ration greater than 1.4. Features that characterized masses as malignant included irregular shape, speculated margins and width to antero-posterior (AP) dimension ratio of 1.4 or less. If these three most reliable criteria had been strictly applied by the primary reporting radiologist, the overall cancer biopsy yield would have increased. The data confirms that certain ultrasound features can help differentiate benign from malignant masses. However, practice and interpreter variability should be further explored before these criteria are applied to defer biopsy of solid masses.
Page(s):
166-169
DOI:
DOI not available
Published:
Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 14, Issue: 3, Year: 2004