Abstract:
The vascular endothelial growth factor is one of the most potent tumor angiogenic factors. The best descriptors with the imperialist competitive algorithm are MATS2m, DISPe, G(O…Cl), RDF090m, Mor30v, and R2u. Masses, electro negativities, van der Waals volumes, the d COMMA2 value, the sum of the geometrical distance between O…Cl and autocorrelations are important in our study. The SMILES files have been used with Coral Sea software. We had: n =5, R²=0.5857, Q²=0.5170, F=4 (Calibration set), n =11, R²=0.9842, Q²=0.9807, F=560 (Training set), n = 5, R² = 0.9999, Q² = 0.9995, F = 25054 (invTrain).
Page(s):
841-844
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 35, Issue: 3, Year: 2022
Keywords:
benzamide derivatives
,
Endothelial cells
,
QSAR
,
CORAL SEA