Total antioxidant capacity, nutritional composition and inhibitory activity of unripe plantain (Musa paradisiacae) on oxidative stress in alloxan induced diabetic rabbits. | [Pakistan Journal of Nutrition • 2010]

Author(s):

1. C. O. Eleazu: Department of Biochemistry, National Root Crops Research Institute, 1 Umudike, Umuahia, Abia State, Nigeria

2. P. N. Okafor: Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Umuahia, Abia State, Nigeria

3. Ikpeama Ahamefuna: Department of Biochemistry, National Root Crops Research Institute, Umudike, Umuahia, Abia State, Nigeria

Abstract:

The antioxidant composition of unripe plantain and its free radical scavenging activity on alloxan induced diabetic rabbits and on DPPH radical was investigated. 10 male rabbits weighing between 1.58 and 1.88 kg were used for this study. Diabetes was induced in the experimental rabbits with alloxan (35 mg/kg body weight. ip). Group 1 rabbits served as the control groups and they received normal rabbit feeds. Group 2 rabbits were the animals of group 1 which were made diabetic by the injection of alloxan and they also received normal rabbit feeds while group 3 rabbits (test groups) were the animals of group 2 which were later fed with unripe plantain at a dosage of 25 kg/kg body weight/day for 4 weeks. The duration of the experiment was 7 weeks and the weights of the animals in each group were recorded daily throughout the experiment while the blood glucose levels, malonaldehyde, catalase and glutathione were recorded on a 2 weeks interval. The results show that the diabetic rabbits placed on unripe plantain diet had an increase in their body weights, glutathione and catalase levels but a decrease in malonaldehyde and blood glucose levels after 4 weeks of unripe plantain intake when compared with the control (p

Page(s): 1052-1057

DOI: DOI not available

Published: Journal: Pakistan Journal of Nutrition, Volume: 9, Issue: 11, Year: 2010

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