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TRPC signaling mechanisms and therapeutic opportunities: Trapdoors are monitored by gatekeepers.
Author(s):
1. Ammad Ahmad Farooqi: Lab for Translational Oncology and Personalized Medicine, Rashid Latif Medical College (RLMC), 35 km Ferozepur Road, Lahore, Pakistan
2. Asma M Riaz: Institute of Molecular Biology & Bio Technology (IMBB), The University of Lahore, Lahore, Pakistan
3. Shahzad Bhatti: Department of Human Genetics and Molecular Biology, University of Health Sciences, Lahore, Pakistan
Abstract:
This Review summarizes our current state of knowledge of the functional role of TRPC channels in health and disease, with particular emphasis on current advancements in the field. Additionally, this review provides an up-to-date summary of SKF-96365 acting on TRPC channels, and discusses strategies to further investigate the potential of these channels for therapeutic intervention.
Page(s): 847-852
DOI: DOI not available
Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 26, Issue: 4, Year: 2013
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