The role of oxygen free radicals in pathogenesis of human amoebiasis. | [Pakistan Journal of Medical Research • 1995]

Author(s):

1. H. Khubnani: Parasitology Department, Postgraduate Institute Medical Education& Research, Chandigarh, India

2. R. C. Mahajan: Parasitology Department, Postgraduate Institute Medical Education& Research, Chandigarh, India

3. R. Sehgal: Parasitology Department, Postgraduate Institute Medical Education& Research, Chandigarh, India

4. K. Singh: Parasitology Department, Postgraduate Institute Medical Education& Research, Chandigarh, India

5. N. K. Ganguly: Parasitology Department, Postgraduate Institute Medical Education& Research, Chandigarh, India

Abstract:

Pathogenesis of amoebiasis is dependent on both host and parasite factors. The present study was undertaken to investigate the role of chemiluminescence response and lysosomal enzymes of blood monocytes in the pathogenesis of amoebiasis. It was observed that in hepatic amoebiasis both chemiluminescence response (810472.0 ± 15996)lysosomal enzyme levels ((510.36 ± 20.99 and 104.57 ± 17.07 for N-acetylgucosaminidase (NAG) and B-glucurominidase (BG) respectively) were increased when compared to normal controls (129244.06 ± 10153.99 chemiluminescence response; 197.05 ± 10.17 NAG and 48.99 ± 2.33 BG; with P

Page(s): 102-105

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical Research, Volume: 34, Issue: 2, Year: 1995

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