Vitamin d deficiency in the patients of diabetes mellitus and its correlation with HbA1c | [Annals of Punjab Medical College • 2023]

Author(s):

1. Anwar Ali Jamali: Peoples University of Medical & Health Sciences for Women, Nawabshah Pakistan

2. Nadeem Ahmed Memon: Department of Medicine, Muhammad Medical College, Mirpurkhas Pakistan

3. Ubaid Rabbani: Department of Medicine, Isra University Hospital, Hyderabad Pakistan

4. Komal: Peoples University of Medical & Health Sciences for Women, Nawabshah (SBA) Pakistan

5. Abdul Karim Soomro: Department of pathology, Bilawal Medical College, Jamshoro, Pakistan

6. Syed Jahanghir: Department of Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

Abstract:

Background: Diabetes mellitus is a prevalent chronic metabolic disorder. Elevated HbA1c levels are associated with a higher risk of diabetes-related complications. Some studies have suggested a potential correlation between vitamin D levels and HbA1c, indicating that vitamin D deficiency may contribute to poor glycemic control. Objective: To evaluate the vitamin d deficiency in the patients of type-II diabetes mellitus and its correlation with HbA1c. Study Design: Crosssectional study. Settings: Department of Medicine, PUMHS Nawabshah and MMC MirpurKhas Pakistan. Duration: 6 months of period from July 2021 to December 2021. Methods: Study included patients with type 2 diabetes mellitus, aged over 40 years and both genders. A 5ml blood sample was collected from each participant after obtaining informed consent and sent to the diagnostic laboratory to determine the HbA1c levels and vitamin D status. Data collection was carried out using a self-made study proforma, and the data were analyzed using SPSS version 26. Results: A total of 58 diabetes patients were evaluated for vitamin D deficient and its correlation with HbA1c. Overall mean age of the patients was 53.32 ± 8.54 years. Males were 28(48.3%) and females were 30(51.7%). Most of the patients 48.30% had moderately decreased vitamin D level, followed by 25.90% cases had mild deficiency, only one case had severely decreased vitamin D level. There was a significant negative correlation between vitamin d level and HbA1c (r= - 0.314) (p= 0.016). Conclusion: Among individuals with type 2 diabetes mellitus, there was a higher prevalence of vitamin D deficiency and insufficiency. Additionally, a significant inverse relationship was observed between vitamin D deficiency and HbA1c levels.

Page(s): 271-274

DOI: 10.29054/APMC/2023.1342

Published: Journal: Annals of Punjab Medical College, Volume: 17, Issue: 3, Year: 2023

Keywords:

Vitamin D , HbA1C , Type2 diabetes mellitus

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