Abstract:
Background: The research was focused on evaluating the safety of a pine tree energy feed additive, a product developed by Himinvest Scientific and Technical Center LLC, located in Nizhny Novgorod, Russia. The need for this study arose from the growing utilization of such feed additives in the agriculture sector and the necessity to ensure their safe usage for livestock health and welfare. Methods: The experiments were carried out on white outbred mice and outbred rats of the Wistar line. The authors conducted a study of acute and chronic toxicity and the local irritant effect of the pine tree energy feed additive. In the experiments, the authors did not establish gender-related differences in the sensitivity of animals to the toxic effect of the preparation. Results: As a result of the conducted studies on white outbred mice, it was found that with a single intragastric injection of the feed additive, it was a relatively harmless substance. Besides, with repeated intragastric administration of the pine tree energy feed additive to outbred rats in subtoxic doses, no significant defects of the functional state of the main organs and systems of the body were observed. Conclusion: The findings suggest that the pine tree energy feed additive is relatively harmless, thus supporting its safe use. No significant toxicity or irritant effects were observed in the test subjects, making it a viable option for feeding purposes.
Page(s):
406-411
DOI:
DOI not available
Published:
Journal: Advancements in life sciences, Volume: 10, Issue: 3, Year: 2023
Keywords:
Safety
,
Additive
,
Pine tree energy feed
,
General toxicity
,
Local irritant effect