A randomized control trial to evaluate the efficacy of a single intravitreal bevacizumab injection before cataract surgery in patients with diabetic macular edema. | [Isra Medical Journal • 2012]

Author(s):

1. Ghulamqadir Kazi: Ophthalmology, Al-Tibri Medical College, Karachi, Pakistan

2. Umer Kazi: Ophthalmology, Al-Tibri Medical College, Karachi, Pakistan

3. Umair Qidwai: Al-Tibri Medical College & Hospital, Isra University, Karachi Campus, Karachi, Pakistan

4. Azfar Nafees: Al-Tibri Medical College & Hospital, Isra University, Karachi Campus, Karachi, Pakistan

5. Asif Kazi: Al-Tibri Medical College & Hospital, Isra University, Karachi Campus, Karachi, Pakistan

6. Munawar Hussain: Al-Tibri Medical College & Hospital, Isra University, Karachi Campus, Karachi, Pakistan

Abstract:

AIMS: To evaluate the efficacy of a single intravitreal Bevacizumab injection before cataract surgery METHODS: Randomised, controlled, open-label, parallel group study of 90 eyes of 90, having diabetic macular edema and lens opacity (of more than grade 3). Change in BCVA at 6 weeks compared with that at baseline. Central macular thickness was compared in both groups pre and post operatively. RESULTS: In Bevacizumab group, 86.7% had BCVA of 6/18 or better and decrease in macular thickness(mean 97 microns), while in control group, only 46.7% had BCVA of 6/18 or better and increased macular thicknes (mean 30 microns) was observed. CONCLUSIONS: Intravitreal Bevacizumab before cataract surgery appears to be beneficial in preventing post- surgical visual loss in eyes with diabetic retinopathy by reducing the chance of macular thickening.

Page(s): 71-75

DOI: DOI not available

Published: Journal: Isra Medical Journal, Volume: 4, Issue: 2, Year: 2012

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