The Role of Hypoglycaemic Agent; Dipeptidyl Peptidase-4 and Its Relation with Biochemical Parameters in Patients With Type-2 Diabetes: A Three Months Trial | [BMC journal of Medical Sciences • 2022]

Author(s):

1. Naghma: Institute of Chemical Sciences, University of Peshawar,Khyber Pakhtunkhwa,Pakistan

2. Rohila Taj: Institute of Chemical Sciences, University of Peshawar,Khyber Pakhtunkhwa,Pakistan

3. Faridullah Shah: Department of Biochemistry, Rehman Medical College,Peshawar, Khyber Pakhtunkhwa,Pakistan

4. Shoukat Sohail: Department of Biochemistry, Ayub Medical College,Abbottabad, Khyber Pakhtunkhwa,Pakistan

5. Asma Shah: Department of Biotechnology, Women University Mardan,Khyber Pakhtunkhwa,Pakistan

6. Mohammad Hashir Ahmad: Department of Biochemistry, Rehman Medical College,Peshawar, Khyber Pakhtunkhwa,Pakistan

7. Mohammad Tayyab Ahmad: Department of Biochemistry, Rehman Medical College,Peshawar, Khyber Pakhtunkhwa,Pakistan

8. Zahoor Ahmed: Department of Biochemistry, Khyber Medical College,Peshawar, Khyber Pakhtunkhwa,Pakistan

Abstract:

Objective: This study was undertaken in order to find out the hypoglycemic control of DPP-4 on the diabetic patients and to evaluate the other related problems. Methodology: A total of 320 type 2 diabetes patients were included in this study. They were treated with oral hypoglycemic drugs. Random as well as fasting blood samples were taken in all hygienic conditions. HbA1c, RBS, FBS, RFTs, serum electrolytes and lipid profiling was carried out by colorimetric methods using kits on Macro Lab 200. The kits were obtained from Elitech, Spain. Fried Wald's formula was used to determine LDL-c. Results: FBS, HbA1C and urea were significantly different (p < 0.05) when compared with base line data while opposite results (p > 0.05) were obtained for RBS, serum total cholesterol, creatinine and TG and serum electrolytes. Conclusion: Risk factors related to diabetes can be reduced by using anti-hyperglycemic agents (DPP-4) on regular basis for a period of three months or more.

Page(s): 34-37

DOI: DOI not available

Published: Journal: BMC journal of Medical Sciences, Volume: 3, Issue: 1, Year: 2022

Keywords:

T2DM , KMC , SGLT1 , Nowshehra , TZDs , ICS , DPP4

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views