Transbronchial Lung Biopsy: Two Years Experience of a Tertiary Care Centre. | [Journal of Postgraduate Medical Institute • 2018]

Author(s):

1. Talha Mahmud: Department of Pulmonology, Shaikh Zayed Hospital & Federal Postgraduate Medical Institute, Lahore - Pakistan

2. Muhammad Saqib: Department of Pulmonology, Shaikh Zayed Hospital & Federal Postgraduate Medical Institute, Lahore - Pakistan

3. Muhammad Aasim: National Health Research Complex, Shaikh Zayed Hospital & Federal Postgraduate Medical Institute, Lahore - Pakistan

Abstract:

Objective: To determine the outcome and safety of transbronchial lung biopsy (TBLB) in various pulmonary disorders. Results: Fifty TBLB procedures yielded results in 45 patients (90%), while 5 (10%) remained inconclusive. Among all patients, pulmonary sarcoidosis was diagnosed in 12 (24%), malignant disease in 9 (18%), pulmonary tuberculosis (PTB) in 5 (10%), chronic hypersensitivity pneumonitis (CHP) in 4 (8%), organizing pneumonia (OP) in 3 (6%), slowly resolving bacterial pneumonia in 5 (10%), non-specific interstitial pneumonia (NSIP) in 4 (8%) and others in 3(6%) of patients. Per procedural bleeding after TBLB occurred in around 13 (30%) but none developed a pneumothorax, hemodynamic instability or death during the procedure. Conclusion: TBLB is a safe bronchoscopic procedure and carries a high diagnostic yield in disorders involving the pulmonary parenchyma.

Page(s): 44-48

DOI: DOI not available

Published: Journal: Journal of Postgraduate Medical Institute, Volume: 32, Issue: 1, Year: 2018

Keywords:

Keywords are not available for this article.

References:

[1] Saqib M, Mahmud T, Khan AM, Ramzan M, Hafeez A, Aasim M. Captain of All These Men of Death - Tuberculosis Remains the Commonest Diagnosis - Two Years Experience of Bronchoscopy at Shaikh Zayed Hospital, Lahore. Proceeding Sheikh Zayed Postgrad Med Inst 2013; 27:81- 6.

[2] HautmannH,HenkeMO,BitterlingH,,2010,High diagnostic yield from transbronchial biopsy of solitary pulmonary nodules using low-dose CT-guidance,Respirology,15,677-

[3] Mahmud T, Saqib M, Mal G. All that Glitters is not Gold. Consolidation, Pyrexia and Leucocytosis. Cryptogenic Organizing Pneumonia mimicking Community Acquired Pneumonia. Pak J Chest Med 2013; 19:158-61.

[4] OstDE,ErnstA,LeiX,KovitzKL,BenzaquenS,Diaz-MendozaJ,,2016,Diagnostic Yield and Complications of Bronchoscopy for Peripheral Lung Lesions. Results of the AQuIRE Registry,Am J Respir Crit Care Med,193,68-77

[5] MahmudT.,,2015,Out of the Fire and into the Fire Again- Advanced Interstitial Lung Disease due to Disseminated Adenocarcinoma Lung,Proceeding Sheikh Zayed Postgrad Med Inst,29,117-21

[6] CloughSY,,2015,Common respiratory symptoms, pulmonary imaging & procedures. American Thoracic Society review for the pulmonary boards;,,,390-

[7] LaiRS,LeeSS,TingYM,WangHC,LinCC,LuJY,,1996,Diagnostic value of transbronchial lung biopsy under fluoroscopic guidance in solitary pulmonary nodule in an endemic area of tuberculosis,Respir Med,90,139-43

[8] Zajaczkowska J.,,1988,Transbronchial lung biopsy in diffuse pulmonary disease,Z Erkr Atmungsorgane,170,132-9

[9] DhooriaS,SehgalIS,AggarwalAN,BeheraD,AgarwalR,,2016,Diagnostic Yield and Safety of Cryoprobe Transbronchial Lung Biopsy in Diffuse Parenchymal Lung Diseases: Systematic Review and Meta-Analysis,Respir Care,61,700-12

[10] MorellF,ReyesL,DoménechG,De GraciaJ,MajoJ,FerrerJ.,,2008,Diagnoses and diagnostic procedures in 500 consecutive patients with clinical suspicion of interstitial lung disease],Arch Bronconeumol,44,185-91

[11] SehgalIS,BalA,DhooriaS,AgrawalP,GuptaN,RamB,,2016,A Prospective Randomized Controlled Trial Comparing the Efficacy and Safety of Cup vs Alligator Forceps for Performing Transbronchial Lung Biopsy in Patients With Sarcoidosis,Chest,149,1584-6

[12] CottinV,CordierJF,,2012,Cryptogenic organizing pneumonia,Semin Respir Crit Care Med,33,462-75

[13] ,2002,This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee,Am J Respir Crit Care Med,165,277-307

[14] SindhwaniG,ShiraziN,SodhiR,RaghuvanshiS,RawatJ,,2015,Transbronchial lung biopsy in patients with diffuse parenchymal lung disease without 'idiopathic pulmonary fibrosis pattern' on HRCT scan - Experience from a tertiary care center of North India,Lung India,32,453-6

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