[1] Biller LH,Schrag DJJ .2021 .Diagnosis and treatment of metastatic colorectal cancer: a review. JAMA, 325(7) : 669-85.
[2] Xi Y,Xu PJTo Y .2021 .Global colorectal cancer burden in 2020 and projections to 2040. , 14(10) : 101174.
[3] Kim JC,Bodmer WFJJocr .2022 .Genomic landscape of colorectal carcinogenesis. Journal of Cancer Research and Clinical Oncology, 148(3) : 533-45.
[4] Ganesh K,Stadler ZK,Cercek A,Mendelsohn RB,Shia J,Segal NH .2019 .Immunotherapy in colorectal cancer: rationale, challenges and potential. , 16(6) : 361-75.
[5] Rompianesi G,Pegoraro F,Ceresa CD,Montalti R .2022 .Artificial intelligence in the diagnosis and management of colorectal cancer liver metastases. World Journal of Gastroenterology, 28(1) : 108.
[6] Zhao Q,Wang F,Chen Y-X,Chen S,Yao YC,Zeng ZL .2022 .Comprehensive profiling of 1015 patients' exomes reveals genomic-clinical associations in colorectal cancer. Nature Communication, 13(1) : 2342.
[7] Nunez SKK,Young CD,Griffen TaL,Ohandjo AQ,McKinney LP,Kopetz S .2021 .. Identification of Gene Co-Expression Networks Associated with Consensus Molecular Subtype-1 of Colorectal Cancer. Cancers, 13(22) : 5824.
[8] Rejali L,Seifollahi Asl R,Sanjabi F,Fatemi N,Asadzadeh Aghdaei H,Saeedi Niasar M .2023 .Principles of Molecular Utility for CMS Classification in Colorectal Cancer Management. , 15(10) : 2746.
[9] Hu F,Wang J,Zhang M,Wang S,Zhao L,Yang H .2021 .Comprehensive analysis of subtype-specific molecular characteristics of colon cancer: Specific genes, driver genes, signaling pathways, and immunotherapy responses. Frontiers in Cell and Developmental Biology, 9 : 758776.
[10] Di Franco S,Bianca P,Sardina DS,Turdo A,Gaggianesi M,Veschi V .2021 .Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery. Nature Communication, 12(1) : 5006.
[11] Purcell RV,Schmeier S,Lau YC,Pearson JF .2019 .Molecular subtyping improves prognostication of Stage 2 colorectal cancer. BMC Cancer, 19(1) : 1-9.
[12] Ten ,de Back TR,Sommeijer DW,Vermeulen LJJJotNCI. .2022 .Clinical value of consensus molecular subtypes in colorectal cancer: a systematic review and meta-analysis. Journal of the National Cancer Institute, 114(4) : 503-16.
[13] Bittoni A,Sotte V,Meletani T,Cantini L,Giampieri R,Berardi RJJCMT .2018 .Immunotherapy in colorectal cancer treatment: actual landscape and future perspectives. Journal of Cancer Metastasis and Treatment, 4(55) : .
[14] Al Zein M,Boukhdoud M,Shammaa H,Mouslem H,El Ayoubi LM,Iratni R .2023 .Immunotherapy and immunoevasion of colorectal cancer. Drug Discovery Today, : 103669.
[15] Baghy K,Ladányi A,Reszegi A,Kovalszky IJIJoMS A .2023 .Insights into the Tumor Microenvironment-Components, Functions and Therapeutics. International Journal of Molecular Sciences, 24(24) : 17536.
[16] Kagawa H,Hatakeyama K,Shiomi A,Hino H,Manabe S,Yamaoka Y .2022 .Consensus molecular subtyping improves the clinical usefulness of canonical tumor markers for colorectal cancer. Biomedical Research, 43(6) : 201-9.
[17] Honkala A,Malhotra SV,Kummar S,Junttila MRJNRDD .2022 .Harnessing the predictive power of preclinical models for oncology drug development. Nature Reviews Drug Discovery, 21(2) : 99-114.
[18] Li J,Zhang A .2022 .Alterations in the gut microbiota and their metabolites in colorectal cancer: recent progress and future prospects. , 12 : 841552.
[19] Rath E,Haller DJMI .2022 .Intestinal epithelial cell metabolism at the interface of microbial dysbiosis and tissue injury. Mucosal Immunology, 15(4) : 595-604.
[20] Mahdavi-Roshan M,Salari A,Kheirkhah J,Ghorbani ZJH,Circulation. ZJH .2022 .The effects of probiotics on inflammation, endothelial dysfunction, and atherosclerosis progression: a mechanistic overview. , 31(5) : e45-e71.
[21] Campbell K,Cawley NX,Luke R,Scott KE,Johnson N,Farhat NY .2023 .Identification of cerebral spinal fluid protein biomarkers in Niemann-Pick disease, type C1. Biomarker Research, 11(1) : 14.
[22] Quaglio AEV,Grillo TG,De Oliveira ECS,Di Stasi LC .2022 .Gut microbiota, inflammatory bowel disease and colorectal cancer. World Journal of Gastroenterology, 28(30) : 4053.
[23] Aghamajidi A,Maleki Vareki SJC .2022 .The effect of the gut microbiota on systemic and anti-tumor immunity and response to systemic therapy against cancer. Cancers, 14(15) : 3563.
[24] Pandey H,Tang DW,Wong SH,Lal DJC .2023 .Gut microbiota in colorectal cancer: biological role and therapeutic opportunities. Cancers, 15(3) : 866.
[25] Pandey P,Khan F,Qari HA,Upadhyay TK,Alkhateeb AF,Oves MJP .2022 .Revolutionization in cancer therapeutics via targeting major immune checkpoints PD-1, PD-L1 and CTLA-4. , 15(3) : 335.
[26] Gaikwad S,Agrawal MY,Kaushik I,Ramachandran S,Srivastava SK .2022 .Immune checkpoint proteins: Signaling mechanisms and molecular interactions in cancer immunotherapy. Seminars in Cancer Biology, 86(3) : 137-150.
[27] Folsom TD,Moriarity BS,Starr TK,Lou E,Webber BRJNCiCIS .2023 .Tumor-infiltrating lymphocytes: Prognostic considerations and current trials as adoptive cell therapy. Elsevier, : 403-26.
[28] Zheng Z,Wieder T,Mauerer B,Schäfer L,Kesselring R .2023 .T Cells in Colorectal Cancer: Unravelling the Function of Different T Cell Subsets in the Tumor Microenvironment. International Journal of Molecular Sciences, 24(14) : 11673.
[29] Andrei P,Battuello P,Grasso G,Rovera E,Tesio N,Bardelli A .2022 .Integrated approaches for precision oncology in colorectal cancer: The more you know, the better. Seminars in Cancer Biology, 84 : 199-213.
[30] Sud R,Mujeeb VR .2022 .Incidence of microsatellite instability, mutational burden, and actionable alterations in genes of patients with metastatic colorectal carcinoma: A Study from a Tertiary Care Hospital in India. Asian Pacific Journal of Cancer Care, 7(1) : 91-100.
[31] .2023 .. Journal of Clinical Investigation, 133(13) : e170762.
[32] Barnestein R,Galland L,Kalfeist L,Ghiringhelli F,Ladoire S,Limagne EJO .2022 .Immunosuppressive tumor microenvironment modulation by chemotherapies and targeted therapies to enhance immunotherapy effectiveness. Oncoimmunology, 11(1) : 2120676.
[33] Satam H,Joshi K,Mangrolia U,Waghoo S,Zaidi G,Rawool S .2023 .Next-generation sequencing technology: Current trends and advancements. Biology, 12(7) : 997.
[34] Manca P,Corti F,Intini R,Mazzoli G,Miceli R,Germani MM .2023 .Tumour mutational burden as a biomarker in patients with mismatch repair deficient/microsatellite instability-high metastatic colorectal cancer treated with immune checkpoint inhibitors. European Journal of Cancer, 187 : 15-24.
[35] Li J,Hu H,Qin G,Bai F,Wu X,Ke H .2024 .Biomarkers of pathologic complete response to neoadjuvant immunotherapy in mismatch repair-deficient colorectal cancer. Clinical Cancer Research, 30(2) : 368-78.
[36] CJJoOPP Chung . .Predictive and prognostic biomarkers with therapeutic targets in colorectal cancer: A 2021 update on current development, evidence, and recommendation. , : .
[37] .2022 .. Journal of Oncology Pharmacy Practice, 28(4) : 850-69.
[38] .2022 .Prognostic and predictive molecular biomarkers in advanced colorectal cancer. Pharmacology & Therapeutics, : 108239.
[39] Ooi Z-S S-W .2022 .RAS and BRAF genes as biomarkers and target for personalised colorectal cancer therapy: An update. Malaysian Journal of Pathology, 44(3) : 415-28.
[40] Patelli G,Mauri G,Tosi F,Amatu A,Bencardino K,Bonazzina E .2023 .Circulating tumor DNA to drive treatment in metastatic colorectal cancer. Clinical Cancer Research, 29(22) : 4530-9.
[41] Pourali G,Khalili-Tanha G,Nazari E,Maftooh M,Nassiri M,Hassanian SM .2023 .Circulating Tumor Cells and Cell-free Nucleic Acids as Biomarkers in Colorectal Cancer. Current Pharmaceutical Design, 29(10) : 748-65.
[42] Schwenck J,Sonanini D,Cotton JM,Rammensee H-G C,Zender L,Bai L,Qiu S-Q,Zhang G-JJST .2023 .Molecular and functional imaging in cancer-targeted therapy: Current applications and future directions. Signal Transduction and Targeted Therapy, 8(1) : 89-490.
[43] Floresta G,Abbate VJMRR .2022 .Recent progress in the imaging of c‐Met aberrant cancers with positron emission tomography. Medicinal Research Reviews, 42(4) : 1588-606.
[44] Hegi-Johnson F,Rudd S,Hicks RJ,De Ruysscher D,Trapani JA,John T .2022 .Imaging immunity in patients with cancer using positron emission tomography. npj Precision Oncology, 6(1) : 24.
[45] Zafari N,Khosravi F,Rezaee Z,Esfandyari S,Bahiraei M,Bahramy A .2022 .The role of the tumor microenvironment in colorectal cancer and the potential therapeutic approaches. Journal of Clinical Laboratory Analysis, 36(8) : e24585.
[46] Li S,Sampson C,Liu C,Piao H-l C,Liu H-XJCC .2023 .Signaling. Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities. Cell Communication and Signaling, 21(1) : 266.
[47] Zhao Y,Shen M,Wu L,Yang H,Yao Y,Yang Q .2023 .Stromal cells in the tumor microenvironment: accomplices of tumor progression? Cell Death and Disease. , 14(9) : 587.
[48] Shakhpazyan N,Mikhaleva L,Bedzhanyan A,Gioeva Z,Sadykhov N,Mikhalev A,Targets Therapeutic .2023 .Cellular and Molecular Mechanisms of the Tumor Stroma in Colorectal Cancer: Insights into Disease Progression. , 11(9) : 2361.
[49] Jiang Q,Huang K,Lu F,Deng S,Yang Z,Hu SJGT .2022 .Modifying strategies for SDF-1/CXCR4 interaction during mesenchymal stem cell transplantation. General Thoracic and Cardiovascular Surgery, 70(1) : 1-10.
[50] Sadri F,Rezaei Z,Fereidouni MJMbr Z .2022 .The significance of the SDF-1/CXCR4 signaling pathway in the normal development. Molecular Biology Reports, 49(4) : 3307-20.
[51] Krasteva N,Georgieva MJP .2022 .Promising therapeutic strategies for colorectal cancer treatment based on nanomaterials. Pharmaceutics, 14(6) : 1213.
[52] Pan Q,Fan X,Xie L,Wu D,Liu R,Gao W .2023 .Nanoenabled colorectal cancer therapy. Journal of Controlled Release, 362 : 548-64.
[53] Lone SN,Nisar S,Masoodi T,Singh M,Rizwan A,Hashem S .2022 .Liquid biopsy: A step closer to transform diagnosis, prognosis and future of cancer treatments. Molecular Cancer, 21(1) : 79.
[54] Heidrich I,Deitert B,Werner S,Pantel KJC,Reviews M. .2023 .Liquid biopsy for monitoring of tumor dormancy and early detection of disease recurrence in solid tumors. Cancer and Metastasis Reviews, 42(1) : 161-82.
[55] Sánchez-Herrero E,Serna-Blasco R,Robado de Lope L,González-Rumayor V,Romero A,Provencio MJFiO A .2022 .Circulating tumor DNA as a Cancer biomarker: an overview of biological features and factors that may impact on ctDNA analysis. Frontiers in Oncology, 12 : 943253.
[56] Mojtaba Mousavi S,Alireza Hashemi S,Yari Kalashgrani M,Rahmanian V,Riazi M,Omidifar N .2024 .Recent Progress in Prompt Molecular Detection of Exosomes Using CRISPR/Cas and Microfluidic‐Assisted Approaches Toward Smart Cancer Diagnosis and Analysis. ChemMedChem, 19(1) : e202300359.
[57] Shi J,Zhang Y,Fan Y,Liu Y,Yang MJD .2024 .; 3(1):e92.. Droplet, : .
[58] Li K,Wu JJTTiAC K .2023 .Recent advances in microfluidic platforms for single particle analysis. TrAC Trends in Analytical Chemistry, : 117139.
[59] Yin Q,Poudel N,Liu ZJTO .2023 .Metabolic reprogramming and cancer progression. Translational Oncology, : 28.
[60] .2023 .; 4(2):e218.. MedComm, : .
[61] .2022 .. Journal of Hematology & Oncology, 15(1) : 160.
[62] Chu Y-D, ,Lim S-N,Lai M-W,Lin WRJCD .2023 .Aldolase B-driven lactagenesis and CEACAM6 activation promote cell renewal and chemoresistance in colorectal cancer through the Warburg effect. Cell Death and Disease, 14(10) : 660.
[63] Coleman O,Ecker M .2022 .Dysregulated lipid metabolism in colorectal cancer. Current Opinion in Gastroenterology, 38(2) : 162-7.
[64] Krauß D,Fari O,Sibilia MJM .2022 .Lipid Metabolism Interplay in CRC-An Update. Metabolite, 12(3) : 213.
[65] Dai W,Mo W,Xu W,Han D,Xu XJA .2023 .Systematic analysis of glutamine metabolism family genes and exploration of the biological role of GPT in colorectal cancer. Aging, 15(21) : 11811.
[66] .2022 .. Frontiers in Molecular Biosciences, 9 : 955705.
[67] Ullah I,Yang L,Yin F-T Y,Li X-H,Li J .2022 .Multiomics approaches in colorectal cancer screening and diagnosis, recent updates and future perspectives. Cancers, 14(22) : 5545.
[68] Pal S,Sharma A,Mathew SP .2022 .Targeting cancer-specific metabolic pathways for developing novel cancer therapeutics. Frontiers in Immunology, 13 : 955476.
[69] Qiu H,Ding S,Liu J,Wang L,Wang XJCO .2022 .Applications of artificial intelligence in screening, diagnosis, treatment, and prognosis of colorectal cancer. Current Oncology, 29(3) : 1773-95.
[70] Waljee AK,Weinheimer-Haus EM,Abubakar A,Ngugi AK,Siwo GH,Kwakye G .2022 .Artificial intelligence and machine learning for early detection and diagnosis of colorectal cancer in sub-Saharan Africa. , 71(7) : 1259-65.
[71] Agarwal S,Yadav AS,Dinesh V,Vatsav KSS,Prakash KSS,Jaiswal SJMTP .2023 .By artificial intelligence algorithms and machine learning models to diagnosis cancer. Materials Today Proceedings, 80 : 2969-75.
[72] .2023 .Artificial intelligence (AI) and machine learning (ML) in precision oncology: a review on enhancing discoverability through multiomics integration. The British Journal of Radiology, 96(1150) : 20230211.
[73] Volovat S-R I,Zob D,Boboc D,Amurariti F,Volovat C .2022 .Use of Personalized Biomarkers in Metastatic Colorectal Cancer and the Impact of AI. , 14(19) : 4834.
[74] Hossain MS,Rahman MM,Syeed MM,Uddin MF,Hasan M,Hossain MA .2023 .(. IEEE Acces, : .
[75] AJDP. AI-Powered Precision Oncology: Computational Insights Redefining Therapeutic Tippur .2023 .Landscapes. DHR Proceeding, 3(S1) : 1-10.
[76] Cripe LD,Vater LB,Lilly JA,Larimer A,Hoffmann ML,Frankel RMJPE .2022 .Goals of care communication and higher-value care for patients with advanced-stage cancer: A systematic review of the evidence. Patient Education and Counseling, 105(5) : 1138-51.
[77] Husebø ALM,Søreide JA,Kørner H,Storm M,Wathne HB,Richardson A .2024 .eHealth interventions to support colorectal cancer patients' self-management after discharge from surgery-an integrative literature review. Supportive Care in Cancer, 32(1) : 11.