Abstract:
Adipose tissue or fat tissue is a loose connective tissue Table-1: Characterisation of three types of adipocytes. that consists mainly of adipocytes. Adipocytes are Characteristics White adipocytes classified on the basis of their secretory origin, differentiation, distribution, cell characteristics, such as Origin Lateral mesoderm amount of mitochondria, size and type of lipid DMiyfffe5rpernetciautrisoonr SNheograttliyveafter birth droplets, and expression of uncoupled protein-1. Lipid droplets Unilocular, large Adipocytes secrete adipokines that are divided as Mitochondria Few mitochondria white adipokines, brown adipokines and beige adipokines. Adipokines have been used as diagnostic Expression of Absent and prognostic markers for different oral diseases. UCP1/Thermogenin Irisin, chemerin, resistin, adiponectin, zinc alpha 2 Residence White depots macroglobulin, leptin, visfatin, tumour necrosis factor- Distribution Adults: alpha and interleukin-6 are some important adipokines Subcutaneous (sWAT), associated with oral diseases, such as dental caries, Visceral (vWAT), periodontal diseases, recurrent aphthous stomatitis, oral cancers, oral premalignant lesions, Sjogren's syndrome, Kawasaki disease and Behcet's disease. The current narrative review was planned to focus on the pathophysiological role of adipokines in oral diseases and their role as biomarkers for early diagnosis and prompt treatment.
Keywords:
Kawasaki disease
,
Adipokines
,
Sjogrens syndrome
,
Oral diseases
,
Brown adipocytes
,
Oral cancers