Wound healing activity of the extracts of Sida acuta. | [Hamdard Medicus • 2005]

Author(s):

1. S. Shanmugam: Department of Pharmaceutics, Melmaruvathur, Tamil Nadu, India

2. M. Senthil Alias Palaniappan: Department of Pharmaceutical Chemistry, Melmaruvathur, Tamil Nadu, India

3. A. Cendilkumar: Adhiparasakthi College of Pharmacy, Melmaruvathur, Tamil Nadu, India

4. T. Vetrichelvan: Adhiparasakthi College of Pharmacy, Melmaruvathur, Tamil Nadu, India

5. S. Hemalatha: Department of Pharmacognosy, Melmaruvathur, Tamil Nadu, India

Abstract:

Leaf extracts of Sida acuta Linn. were screened for wound healing activity in types of wound models in rats (I) Excision and (2) Incision wound model. Complete filling and healing of wounds was observed for 12 days after daily application of the aqueous and alcoholic extracts in the form of an ointment in the concentration of 5% w/w and 10% w/w. Both alcoholic and aqueous extracts of the plant produced a significant response in wound healing. The results were also comparable to standard drug Povidone Iodine ointment in terms of wound contracting ability; percentage wound closure and tensile strength.

Page(s): 76-79

DOI: DOI not available

Published: Journal: Hamdard Medicus, Volume: 48, Issue: 1, Year: 2005

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