A rare case eumycetoma: Successful treatment with itraconazole | [Journal of Pakistan Association of Dermatologists • 2023]

Author(s):

1. Rusmawardiana: Department of Dermatology and Venereology Medical Faculty of Sriwijaya University/ Dr. Mohammad Hoesin General Hospital Palembang, South Sumatra, Indonesia.

2. Fifa Argentina: Department of Dermatology and Venereology Medical Faculty of Sriwijaya University/ Dr. Mohammad Hoesin General Hospital Palembang, South Sumatra, Indonesia.

3. Raden Pamudji: Department of Dermatology and Venereology Medical Faculty of Sriwijaya University/ Dr. Mohammad Hoesin General Hospital Palembang, South Sumatra, Indonesia.

4. Putri Laksmi Karim: Department of Dermatology and Venereology Medical Faculty of Sriwijaya University/ Dr. Mohammad Hoesin General Hospital Palembang, South Sumatra, Indonesia.

Abstract:

Eumysetoma is a chronic infectious disease characterized by an enlarged subcutaneous mass, often caused by the fungus Madurella mycetomatis. Eumycetoma can affect all age groups, but often occurs in young people between 20 and 40 years, in children rarely 3-4.5% but can be up to 30% of cases, dominant in males with a ratio of 4:1, mainly working agricultural activities. Treatment of eumycetoma with medication antifungal group Triazola (Itraconazole) and surgery are the therapy of choice. We report a case of eumycetoma treated with itraconazole. A 57-year-old man with complaints of progressive chronic wounds. Dermatological status showed multiple nodules, there were sinuses with discharge and grain on the feet. Histopathological examination revealed suppurative granuloma and Splendore-Hoeppli phenomenon in the dermis layer. The patient was diagnosed with eumycetoma and treated with itraconazole 2x200mg. Administration of itraconazole 2x400 therapy in eumycetoma patients is effective and provides clinical improvement.

Page(s): 736-740

DOI: DOI not available

Published: Journal: Journal of Pakistan Association of Dermatologists, Volume: 33, Issue: 2, Year: 2023

Keywords:

Itraconazole , Abstract , eolgtEumycetoma , Madurella mycetomatis

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