The antimicrobial activity of essential oils and extracts of some medicinal plants grown in Ash-shoubak region – South of Jordan. | [Pakistan Journal of Pharmaceutical Sciences • 2012]

Author(s):

1. Mohammad Sanad Abu-Darwish: Department of Basic and Applied Sciences, Al-Shouback University College, Al-Balqa` Applied University, Jordan

2. Ezz Al-Dein Muhammed Al-Ramamneh: Department of Agricultural Sciences, Al-Shouback University College, Al-Balqa` Applied University, Jordan

3. Viktoria Sergeevna Kyslychenko: Department of Chemistry of Natural Compounds, National Pharmaceutical University, 53 Pushkin St, Kharkiv, Ukraine

4. Uliana Vladimirovna Karpiuk: Department of Pharmacognosy & Botany, National OO Bohomolets Medical University, 13 T. Shenchenko Boulevard, Kiev, Ukraine

Abstract:

The inhibitory effects of essential oils as well as chloroformic extracts of Thymus vulgaris, Thymus serpyllum, Salvia officinalis and Pimpinella anisum grown in Ash-shoubak region–south of Jordan and their possible individual phytochemical constituents was screened against pathogenic clinical and standard strains of Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. The bioassay employed was the agar well diffusion method. The essential oils and chloroformic extracts of T. vulgaris and T. serpyllum were the most effective against the tested strains of bacteria. Clinical and standard strains of S .aureus and P. aeruginosa were uninhibited by S. officinalis essential oils. P. aeruginosa tested strains were also resistant to P. anisum essential oils. For almost all bacterial strains, the highest antibacterial effect of oils was obtained with the highest tested dose (15 µl). Chlorformic extracts of S. officinalis showed small activity against standard and clinical E. coli strains and were not effective to inhibit strains of P. aeruginosa and S. aureus. Chloroformic extracts obtained from P. anisum and applied at 300 µg/cm³ slightly inhibited E. coli, but moderately inhibited S. aureus. It is shown from the results that the antibacterial effects of the individual components varied depending upon their chemical structure, functional groups and configuration as well as doses used. This study showed the beneficial effects of the essential oils of T. serpyllum and T. vulgaris grown in Ash-shoubak in inhibiting the growth of microbes and the implications this could have in pharmacy and food technology.

Page(s): 239-246

DOI: DOI not available

Published: Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 25, Issue: 1, Year: 2012

Keywords:

Keywords are not available for this article.

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views