Acute Hepatitis in Children: Experience at a Tertiary Hospital of Bangladesh | [Pakistan Paediatric Journal • 2019]

Author(s):

1. MD BENZAMIN: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

2. MAIMUNA SAYEED: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

3. MUKESH KHADGA: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

4. Khan Lamia Nahid: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

5. Md Rukunuzzaman: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

6. Md Wahiduzzaman Mazumder: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

7. Fahmida Begum: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

8. Md. Saidul Islam: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

9. Maria Kibtiar: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

10. A S M Bazlul Karim: Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh

Abstract:

Objective: Evaluation of etiological spectrum and outcome of children with acute hepatitis in a tertiary care hospital. Study Design: Retrospective observational study Place and Duration of Study: This study was conducted at the Department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from January 2015 to January 2018 Material and Methods: This study included 161 admitted children; age between 5 months to 16 years who were diagnosed as acute hepatitis. Results: Mean age (years) of children was 8.14±3.11, range 0.5-16 years. About 91.3% were acute viral hepatitis. Most common etiologies were hepatitis A virus (HAV) (70.9%), then hepatitis E virus (HEV) (8%), HAV with HEV co-infection (3.7%), Salmonella hepatitis (6.3%), enteric fever with HAV co-infection (3.2%), drug induced hepatitis (antiTB) (2.4%) and others. Anicteric hepatitis was 7.5%. Conclusion: Acute hepatitis is a common problem in children, HAV and HEV is the most common etiology. Dual infections, like HAV with HEV co-infection and enteric fever with co-infection are not uncommon.

Page(s): 265-269

DOI: DOI not available

Published: Journal: Pakistan Paediatric Journal, Volume: 43, Issue: 4, Year: 2019

Keywords:

Children , Viral Hepatitis , Salmonella Hepatitis , Anicteric Hepatitis

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