A simple and efficient synthesis of some important Pyrazole derivatives. | [Journal of Chemical Society of Pakistan • 2015]

Author(s):

1. Elif Korkusuz: Kayseri Vocational College, Erciyes University, 38039, Kayseri, Turkey

2. Ismail Yildirim: Department of Chemistry, Faculty of Sciences, Erciyes University, 38039, Kayseri, Turkey

Abstract:

The 1H-pyrazole-3-carboxylic acid was converted via reactions of its acid chloride 1a;b with amino acid; thiol and various amine derivatives into the corresponding amino acid ester derivatives 2a-d; 4-aroyl-1;5-diaryl-1H-pyrazol-3-carbotioates 3a-d; and pyrazole-3-carboxamides 6; 7 respectively; in good yields (35-85%). The structures of all new synthesized compounds were established by the 13C NMR; 1H NMR; IR spectroscopic data and elemental analyses.

Page(s): 1177-1184

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 37, Issue: 6, Year: 2015

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