Testicular Choriocarcinoma: diagnosed on cervical lymph node biopsy. | [Journal of Pakistan Medical Association • 2013]

Author(s):

1. Nadeem Zia Abbasi: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

2. Zainab Zahur: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

3. Abdul Samad Sheikh: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

4. Amjad Aziz Khan: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

5. Fayyaz Ahmed: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan Bio-Sciences Division, PAEC HQ, Islamabad, Pakistan

6. Khalid Hussain Memon: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

7. Furqan Ali: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

8. Asif Jeilani: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

9. Tetheer Fatima: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

10. Kamran Khan: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

11. Attia Gul: Department of Oncology, Institute of Nuclear Medicine, Oncology and Radiotherapy (INOR), Abbottabad, Pakistan

Abstract:

Choriocarcinoma is a very rare germinal testicular tumour and in literature its incidence has been reported to be 0.3% of all germinal testicular tumours. An important tumour marker is serum ß-hCG which not only helps in establishing diagnosis but also in assessing response to chemotherapy. In this study we present a case of testicular choriocarcinoma, who presented with abdominal pain, cough, generalized weakness and left sided cervical mass. Incisional biopsy of cervical mass was performed. Histopathology revealed metastatic choriocarcinoma. Serum ß-hCG levels were 1227 ng/mL. Patient received intravenous cycles of PEB (cisPlatin, Etoposide, Bleomycin) chemotherapy but he had progressive disease both radiologically and on tumour marker monitoring. He was planned for salvage chemotherapy but was lost to follow up there after. It is concluded that in males, choriocarcinoma carries a very dismal prognosis and a very poor response to chemotherapy and radiotherapy; surgery has no role in the management.

Page(s): 1544-1546

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 63, Issue: 12, Year: 2013

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